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Published on: 4/28/2025

At What Age Does Menopause-Related Brain Fog Typically Begin?

Menopause-related brain fog often begins during perimenopause, typically when women are in their mid-40s to early 50s.

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Explanation

Many women notice problems with memory and concentration, known as brain fog, as they start transitioning into menopause. This time is called perimenopause and can usually begin in the mid-40s and continue into the early 50s. During perimenopause, hormone levels change, particularly the decline in estrogen, which may affect the way the brain works. Women might find that it is harder to focus on tasks, remember names or words, or keep track of daily activities. Research shows that these cognitive changes are common in midlife and can vary from one person to another. Some women experience mild brain fog, while others may notice a bit more disruption in their daily activities. It is important to remember that these changes are a normal part of the transition. If these symptoms become concerning or disruptive, talking with a healthcare provider can be helpful. Often, simple strategies like better sleep, physical activity, and brain exercises might ease some of these cognitive difficulties during the menopausal transition.

(References)

  • Conde DM, Verdade RC, Valadares ALR, Mella LFB, Pedro AO, Costa-Paiva L. Menopause and cognitive impairment: A narrative review of current knowledge. World J Psychiatry. 2021 Aug 19;11(8):412-428. doi: 10.5498/wjp.v11.i8.412. PMID: 34513605; PMCID: PMC8394691.

  • Maki PM, Jaff NG. Menopause and brain fog: how to counsel and treat midlife women. Menopause. 2024 Jul 1;31(7):647-649. doi: 10.1097/GME.0000000000002382. Epub 2024 Jun 17. PMID: 38888619.

  • Metcalf CA, Duffy KA, Page CE, Novick AM. Cognitive Problems in Perimenopause: A Review of Recent Evidence. Curr Psychiatry Rep. 2023 Oct;25(10):501-511. doi: 10.1007/s11920-023-01447-3. Epub 2023 Sep 27. PMID: 37755656; PMCID: PMC10842974.

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