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Published on: 7/15/2026
Chest pain accompanied by night sweats may signal a serious underlying condition, including heart-related issues (such as a heart attack or angina) or lung problems like a pulmonary embolism. Other possible causes include infections, acid reflux, anxiety, or hormonal changes. Because these symptoms can overlap with life-threatening conditions, they should never be ignored.
If you're experiencing chest pain and night sweats, understanding the potential cause quickly is critical. A free, instant, online symptom check can help you evaluate your symptoms in minutes, identify possible conditions, and guide your next steps—whether that means seeking emergency care, scheduling a doctor's visit, or monitoring at home. Taking a few moments now could make a meaningful difference in your health outcome.
Reviewed for medical accuracy: 07/14/2026
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Submit your own QuestionWhen you feel chest pain and notice sweating at night, it might be more than just a simple cold or muscle strain. One possibility is that your heart isn't getting enough blood because of a heart problem like coronary heart disease. Sometimes, these heart issues show up with symptoms like pain and sweating, even when you're sleeping. Another heart-related concern is a heart attack, which needs immediate help. On the lung side, there is a condition called a pulmonary embolism, which is a blood clot in the lung. This can cause chest pain, difficulty breathing, and sweating, even at night. Other medical conditions, including infections or hormonal changes, might also cause these symptoms. Because the chest pain and sweating combination can be a sign of something serious, you can use Ubie's free AI-powered symptom checker to help identify possible causes and understand when to seek immediate medical attention. Your doctor may use tools like blood tests, imaging studies, and heart monitoring to figure out the cause and help decide the best treatment for you.
(References)
Feher A, Muhsin SA, Maw AM. Night Sweats as a Prominent Symptom of a Patient Presenting with Pulmonary Embolism. Case Rep Pulmonol. 2015;2015:841272. doi: 10.1155/2015/841272. Epub 2015 May 11. PMID: 26078907; PMCID: PMC4442258.
Herber-Gast G, Brown WJ, Mishra GD. Hot flushes and night sweats are associated with coronary heart disease risk in midlife: a longitudinal study. BJOG. 2015 Oct;122(11):1560-7. doi: 10.1111/1471-0528.13163. Epub 2014 Nov 7. PMID: 25377022.
Wuyts L, Pouillon M, Huyghe M, Ruyssers N, Goovaerts G, Spaepen M. Palpitations, headache and night sweats caused by a retroperitoneal mass: case report and short review. BJR Case Rep. 2017 Aug 2;3(4):20170035. doi: 10.1259/bjrcr.20170035. PMID: 30363222; PMCID: PMC6159177.
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