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It can start the same day or a few days later: acute nausea often begins during treatment or within 1 to 6 hours, while delayed nausea commonly appears 1 to 5 days afterward, peaking around days 2 to 3; with modern prevention, many people have little or no nausea. There are several factors to consider, including the drugs and doses you receive, your past nausea or motion sickness, and how you take prescribed anti-nausea medicines. See below for drug specific timing, how long symptoms typically last, practical tips, and when to call your care team urgently.

Both are possible: many people feel nausea the same day, often peaking about 5 to 6 hours after chemotherapy, while delayed nausea typically starts 1 to 3 days later and can last up to 5 days. There are several factors to consider, including the specific drugs, your age and sex, prior motion or morning sickness, and the antiemetics you use; prevention and rescue strategies differ by phase and can guide your next steps. See below for details on timing, the best medicines to ask about, non-drug options, and warning signs that mean you should call your care team.

While on chemotherapy, seek urgent medical care for any fever 100.4°F (38°C) or higher, chills, shortness of breath or chest pain, a rapidly worsening cough or phlegm that is yellow, green, or bloody, severe sore throat or trouble swallowing, dehydration or inability to eat or drink, confusion, severe headache, or fainting. Mild congestion, clear runny nose, and a mild sore throat without fever can often be managed at home, but there are several factors to consider; see below for a complete checklist of red flags, safe home remedies, and guidance on when to call your oncology team or go to the ER.

Constipation is common during chemotherapy and often stems from opioid pain medicines, anti-nausea drugs, dehydration, low fiber intake, reduced activity, electrolyte imbalances, nerve changes, or bowel narrowing from tumors or prior surgery. There are several factors to consider; see below to understand more. Relief usually comes from fluids, gradual fiber, gentle movement, a regular toilet routine and positioning, plus OTC laxatives like polyethylene glycol or senna, with prescription options such as lubiprostone or PAMORAs for opioid-related cases; seek urgent care for severe pain, vomiting, bleeding, or no bowel movement for 5 to 7 days, and see complete steps below.

Diarrhea during chemotherapy can often be managed at home if symptoms are mild fewer than 4–5 loose stools a day, no fever, you can keep fluids down, and things improve with hydration, gentle foods, and approved anti-diarrheals. Seek urgent care for six or more loose stools in 24 hours, diarrhea lasting more than 24–48 hours, fever, blood or black stool, severe belly pain, signs of dehydration like dizziness or very little urine, or inability to keep fluids down; fever with low white counts or immunotherapy-related diarrhea are emergencies. There are several factors to consider, and important details that could change your next steps are explained below.

Not everyone loses their hair during chemotherapy; the risk and severity vary by the drugs used, their doses and schedules, combinations, and your individual sensitivity. There are several factors to consider, including options like scalp cooling to reduce loss and the typical timeline and likelihood of regrowth after treatment; see below for drug-specific risks, timing, prevention strategies, and when to talk with your care team.

Extreme fatigue during chemotherapy is very common and often due to cancer related fatigue, but there are several factors to consider. It can also signal treatable problems such as anemia, infection, dehydration, medication effects, thyroid or adrenal disorders, or liver and kidney dysfunction. Patterns around treatment timing, red flag symptoms like fever, jaundice, chest pain or palpitations, and tests such as a CBC and liver or kidney panels help sort side effect from something else, so see the complete guidance below for what to watch for, when to call your team, and practical steps to feel better.

Extreme fatigue during chemotherapy is common and usually an expected side effect, but if it is sudden, severe, or limiting basic activities it can point to anemia, infection, electrolyte or thyroid issues, heart or lung problems, medication effects, or chemotherapy-related skin toxicity. There are several factors to consider. See below for specific red flags like shortness of breath, chest pain, fever, confusion, and skin changes, plus how doctors evaluate fatigue and practical steps that can guide your next decisions.

Chemotherapy can cause thinning or loss of eyebrows, eyelashes, and body hair starting 2 to 4 weeks into treatment, with regrowth usually beginning 4 to 6 weeks after it ends and continuing over 6 to 12 months, sometimes with changes in texture or color. There are several factors to consider, including your drug regimen, gentle care and cosmetic strategies, and the limits of prevention such as scalp cooling helping scalp hair but not brows or lashes; see below for specific tips, timelines, and when to contact your care team.

During chemotherapy, an oral temperature of 38.3 °C or 101.0 °F once, or 38.0 °C or 100.4 °F for more than one hour, is an emergency; contact your oncology team immediately or go to the emergency department. Even without fever, urgent signs like shaking chills, trouble breathing or chest pain, confusion or fainting, a very fast heart rate or low blood pressure, severe abdominal symptoms or vomiting, painful urination, or redness around a port or catheter need immediate care. There are several factors to consider, so see the complete details below.

You can go out during chemotherapy, but there are several factors to consider, including your specific regimen, current blood counts, other health conditions, and local infection rates. Plan outings for safer windows when counts have recovered, favor outdoor or uncrowded activities, practice hand hygiene and indoor masking, and call your oncology team promptly for fever or new symptoms; see below for key details on timing, lower risk options, vaccinations, red flags, and when to postpone plans.

It usually begins 2 to 4 weeks after the first chemotherapy infusion, often accelerates after the second or third treatment, peaks around weeks 4 to 6, and regrowth typically starts 3 to 6 months after finishing therapy. There are several factors to consider, including the drug type and dose, treatment schedule, individual differences, and preventive options like scalp cooling. See below for important details that can affect your next steps, such as how to prepare, ways to reduce shedding, and when to contact your care team.

There are several proven ways to reduce vein pain during chemotherapy infusions. Options include lidocaine pretreatment or topical numbing, warm compresses and good hydration, slower infusion rates or dilution, careful vein selection and secure IV placement, relaxation and distraction, oncologist-approved pain relievers, and considering a port or PICC. There are several factors to consider, and it is vital to recognize red flags like persistent burning pain, swelling, redness or blistering, numbness, fever, or signs of infection; see below for complete details and which next steps to take with your oncology team.

Yes, it is usually okay and often helpful to eat; small, frequent bites of bland or cool foods with steady fluids can settle your stomach, while greasy, spicy, strong-smelling, or acidic foods may worsen symptoms, and anti-nausea medicines should be taken as prescribed. There are several factors to consider, including when to pause eating and call your oncology team if you have active vomiting or cannot keep fluids down; see below for specific food and drink suggestions, timing tips, hydration guidance, and other warning signs that may change your next steps.

Yes, it is generally okay to eat when you feel nauseated during chemotherapy, but there are several factors to consider; small, frequent, bland or cool foods plus steady sips of fluids and taking prescribed anti-nausea medicines can make eating more tolerable, and timing meals around your worst nausea can help. If vomiting is severe, start with clear liquids, advance to soft foods, and reintroduce solids slowly, and call your care team for uncontrolled vomiting, dehydration signs, or notable weight loss; see below for important details on specific foods, hydration strategies, ginger and other aids, when to pause solids, and exactly when to seek medical help.

There are several factors to consider: many chemotherapy side effects are expected and manageable, but call your care team the same day for persistent vomiting, diarrhea lasting more than 24 hours, painful mouth sores, unusual bruising, worsening numbness or tingling, new swelling, rash, or burning with urination. Seek urgent care now for fever 100.4°F or higher, chills, shortness of breath or chest pain, sudden confusion or severe headache, uncontrolled bleeding, black or bloody stools, severe abdominal pain, fainting, or sudden one-sided weakness. Important nuances about blood counts and skin changes like hand foot syndrome can affect what you should do next, so see the complete guidance below.

Serious chemo side effects needing immediate ER care include fever in neutropenia, chest pain, severe shortness of breath, sudden confusion or seizures, uncontrolled bleeding, signs of anaphylaxis, or severe dehydration. There are several factors to consider; key red flags and what to do next are outlined below. Call your oncology team today for fever of 100.4 F or higher without known neutropenia, persistent vomiting or diarrhea, severe pain not controlled by medication, infection signs at lines or with urination or cough, or symptoms of low blood counts; milder issues like mild nausea, fatigue, mouth sores, skin changes, and mild neuropathy can often be managed at home while monitoring. Important thresholds, system-specific tips, and when to escalate care are explained below.

Loss of appetite during chemotherapy is common; practical steps include small, frequent meals, calorie and protein dense foods, and sipping smoothies or nutrition drinks, with simple adjustments for taste changes, nausea, and mouth sores. Know when to call your care team, such as if you cannot eat or drink for 24 to 48 hours, show signs of dehydration, have persistent vomiting, rapid weight loss, fever, or painful sores, since medicines, supplements, and dietitian support can help. There are several factors to consider; see below for complete guidance that could affect your next steps.

Loss of appetite during chemotherapy is common and manageable with small, frequent, nutrient-dense meals, cold or room-temperature foods if smells trigger nausea, flavor adjustments for taste changes, and steady hydration. If eating remains difficult, your care team can use anti-nausea medicines, appetite stimulants like megestrol or dronabinol, and oncology dietitian support, and you should seek prompt care for rapid weight loss, dehydration, or persistent vomiting. There are several factors to consider. See important details below to guide your next steps.

A drop in white blood cells during chemotherapy raises infection risk; seek help promptly for any fever of 100.4°F or higher, chills, new cough or breathing trouble, mouth sores, burning with urination, red or warm skin, or persistent vomiting or diarrhea. There are several prevention and treatment steps to consider, including strict hand hygiene, avoiding crowds and risky foods, and care-team options like growth factor shots, antibiotics, or chemo schedule changes; febrile neutropenia can be an emergency, so see below for important details that can guide your next steps.

Arm pain after chemotherapy is common, often from chemotherapy-induced peripheral neuropathy, catheter or port problems like infection or clots, lymphedema, or musculoskeletal strain, but seek urgent care for red flags such as fever, sudden one-sided swelling, rapidly worsening pain or numbness, chest pain, shortness of breath, or new weakness. There are several factors to consider. See below for how to recognize the likely cause, home care that can help, and the exact signs that mean you should contact your oncology team or go to urgent care.

Hair often starts to fall out 1 to 3 weeks after chemo begins, so plan before your first infusion by talking with your care team about your regimen and scalp-cooling options. Consider a shorter cut, gentle hair and scalp care, sun protection, and arranging wigs or soft head coverings plus emotional support; below you will find step-by-step guidance, cost and insurance tips, fabric and product recommendations, and specific signs that mean you should call your doctor.

Severe pain during chemotherapy does not automatically mean you need to stop; many patients continue treatment with dose adjustments, drug switches, and targeted pain control based on the pain type, severity, and treatment goals. There are several factors to consider. See below for detailed options, red flags that need urgent care, and step by step guidance to decide whether to adjust, delay, or continue treatment safely with your care team.

Severe pain during chemotherapy usually does not require stopping treatment, but it should never be ignored; the cause and severity guide whether to adjust the dose, switch drugs, pause briefly, or add pain control. There are several factors to consider. See below to understand more. Contact your oncology team now, and seek urgent care if pain comes with fever or chills, chest pain, trouble breathing, confusion or new weakness, uncontrolled vomiting or diarrhea, or blistering skin, since these can be emergencies. Early evaluation can prevent long term damage and help you continue therapy more safely.

There are several factors to consider: most people do best with a balanced plan that combines gentle, regular activity with adequate rest, set with your oncology team, and you should pause and prioritize rest if you develop red flags like fever, chest pain, severe shortness of breath, heavy bleeding, or low blood counts. See below for specific safe exercise targets, when to rest, and practical tips on sleep, nutrition, stress, and energy conservation that could influence your next steps.

The healthiest approach is a balance of planned rest and gentle activity, guided by your body and care team, resting when symptoms are severe and moving lightly when you feel up to it. There are several factors to consider, including energy pacing, red flags that require medical attention, and the roles of sleep, nutrition, emotional support, and skin symptoms, so see below for important details that can shape your next steps.

Feeling exhausted but unable to sleep during chemotherapy is common and usually stems from a mix of circadian rhythm disruption, inflammation, steroids or other meds, physical side effects like pain or hot flashes, and stress, anxiety or depression. There are several factors to consider and targeted steps that can help, from sleep routine changes, morning light and gentle activity to medication timing, CBT-I and safe short-term aids like melatonin, plus red flags that need urgent care; see the complete guidance below to understand what applies to you and which next steps to take with your oncology team.

Call your oncology team promptly if vomiting occurs more than 3 to 4 times in 24 hours, does not improve with prescribed anti-nausea medicine, you cannot keep liquids down for 24 hours, or you have signs of dehydration, severe abdominal pain, or blood in the vomit. Seek emergency care for vomiting with fever 100.4°F or higher, confusion or severe weakness, chest pain, trouble breathing, severe headache, signs of bowel blockage, or sudden swelling or rash; mild vomiting that improves with meds and fluids may be managed at home, but there are several factors to consider and important details that could change your next steps, so see the complete guidance below.

There are several factors to consider; see below to understand more, but in general a chemo port is recommended for long term or frequent chemotherapy, when drugs are harsh on veins, IV access is difficult, blood draws are frequent, or combination infusions are planned. It may not be needed for short, mild, or oral regimens if veins are easy, but potential risks like infection or clots and your preferences matter, so discuss with your oncology team and review the details below to guide your next steps.

A CV port is typically recommended for long-term therapy beyond 4 to 6 months, frequent or weekly infusions, vesicant chemotherapy, difficult veins, regular blood draws, high-dose chemo or stem cell transplant, or long-term TPN. There are several factors to consider. Active infection, severe bleeding risk, very short-term therapy, or certain anatomy may make other access better, and conditions like cirrhosis require careful risk assessment. See the complete details below to understand benefits, risks, and how to decide with your oncology team.