What could cause pain in the area between my testicles and anus?

Reviewed by Yoshinori Abe, MD

Internal Medicine

Pain between the testicles and anus—an area known as the perineum—is often caused by myofascial trigger points, chronic prostatitis, or infections. Other possible causes include pudendal nerve irritation, pelvic floor dysfunction, or injury from prolonged sitting or cycling. Because symptoms can overlap across conditions, identifying the exact cause typically requires a careful evaluation.

If you're experiencing perineal pain, don't guess or wait it out. Understanding the likely cause is the fastest way to get relief and know whether you need urgent care, a specialist, or simple at-home measures. Take a free, instant, online symptom check to get personalized insight into your symptoms and clear guidance on your next steps.

Reviewed for medical accuracy: 07/15/2026

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Explanation

Pain in the area between the testicles and anus, known as the perineum, can have several causes. One possible reason is the presence of painful myofascial trigger points. These are sensitive areas in the muscles that can cause pain and discomfort.

Another potential cause is chronic prostatitis, a condition that affects the prostate gland and can lead to pain in the perineal region. Other perineal, rectal or genital infections can cause pain in the this region and need to be urgently addressed by a healthcare provider.

If you are experiencing persistent pain, you can start by using our free AI symptom checker to help identify possible causes, and then consult a healthcare professional for a proper diagnosis and treatment plan.

(References)

Anderson RU, Sawyer T, Wise D, Morey A, & Nathanson BH. (2009). Painful myofascial trigger points and pain sites in men with .... The Journal of urology, 19837420.
Shafik A, & El-Sibai O. (2000). The anocavernosal erectile dysfunction syndrome. II Anal .... International journal of impotence research, 11424966.
Ying J, Zhou MJ, Chen HY, Chen L, Zhang W, Ji J, et al. (2019). Effect of Essential Oil on Patients with Chronic Prostatitis .... Chinese journal of integrative medicine, 29948596.

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