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Published on: 12/17/2025
There are several factors to consider: sudden right‑side armpit pain is often from muscle strain, swollen lymph nodes, or skin issues, but can also arise from shingles or nerve irritation, or be referred from deeper conditions like gallbladder disease, liver/diaphragm irritation, atypical heart symptoms, or (rarely) a lung apex tumor. Seek urgent care for severe or unexplained pain, fever/redness or pus, a hard or rapidly enlarging lump, chest tightness/shortness of breath or sweating, jaundice, or new arm weakness/numbness. See below for key details that can guide your next steps, including what to watch for, home care, prevention, and when to call a doctor.
Understanding Pain Under the Right Armpit in Women
Sudden pain under the right armpit (axilla) in a woman can be unsettling. While many causes are harmless and self‐limited, some warrant prompt medical attention. This guide covers common and uncommon triggers, what to watch for, and when to speak to a doctor.
Common, Benign Causes
Muscle Strain or Overuse
– Heavy lifting, awkward arm movements or intense workouts can strain the muscles around the shoulder and chest wall, leading to aching or sharp pain under the armpit.
– Usually improves with rest, ice, gentle stretching and over‐the‐counter pain relievers.
Swollen Lymph Nodes
– Lymph nodes in the axilla filter fluid and fight infection.
– Colds, skin infections (like a small cut or insect bite), or even a recent vaccination can cause temporary enlargement and tenderness.
– Look for a small, soft lump that feels mobile under the skin.
Skin Conditions
– Folliculitis (inflamed hair follicles) or hidradenitis suppurativa (blocked sweat glands) can cause painful, red bumps.
– Warm compresses and good hygiene often help; severe cases may need antibiotics or dermatology referral.
Epidermal Cysts and Lipomas
– Benign, slow‐growing lumps under the skin.
– Usually painless unless inflamed or infected. A doctor can confirm and remove if bothersome.
Shingles (Herpes Zoster)
– Reactivation of chickenpox virus along a nerve can cause burning pain, tingling, then a blistering rash in a stripe pattern—sometimes under the armpit.
– Early antiviral treatment (within 72 hours of rash onset) lessens severity.
Neuralgic Amyotrophy (Parsonage-Turner Syndrome)
– Sudden, severe shoulder‐arm pain often followed by muscle weakness.
– van Alfen & van Engelen (2006) describe this condition’s key features:
• Intense, sharp pain around the shoulder that can radiate to the axilla
• Onset often without trauma or after a viral illness
• Recovery may take months; physical therapy can aid rehabilitation.
Referred or Deeper Pain
Pain felt in the armpit may originate from structures deeper in the chest or abdomen.
Gallbladder Disease
• Gallstones or inflammation (cholecystitis) typically cause right upper‐quadrant pain.
• Pain may radiate under the right shoulder blade or into the axilla.
• Often triggered after fatty meals, accompanied by nausea or mild fever.
Liver or Diaphragm Irritation
• Liver enlargement or inflammation (hepatitis, congestion) can press on the diaphragm.
• Discomfort may be felt in the upper abdomen or radiate toward the right shoulder/axilla.
• Chronic liver disease patients (Chon et al., 2012; Kamath & Kim, 2007) may note dull aches, but acute sharp pain is less common.
Lung Apex Tumors (Pancoast Tumor)
• Rare, but a tumor at the lung’s top can invade nerves supplying the shoulder and axilla, causing persistent pain, sometimes with arm weakness or numbness.
Cardiac Ischemia
• While left‐sided chest pain is classic, heart issues can sometimes present atypically with right‐sided discomfort, including the axilla—especially in women or diabetics.
• Associated symptoms: shortness of breath, sweating, dizziness.
When to Seek Urgent Medical Care
Most armpit pain resolves on its own or with basic treatment. However, see a doctor immediately if you experience:
If you’re unsure, you might consider doing a free, online symptom check for guidance on next steps.
At‐Home Care Tips
Preventing Future Episodes
Key Takeaways
Your health matters. If your right‐side armpit pain is severe, persistent or accompanied by concerning symptoms, please speak to a doctor without delay.
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