Published on: 4/7/2025
Perineum pain in males is usually not a sign of cancer, but in some cases, especially when combined with other symptoms like changes in urination or unexplained weight loss, it could be a warning sign that needs further evaluation.
In many cases, pain in the perineum—the area between the scrotum and anus—is caused by non-cancer issues like prostatitis or other benign conditions. However, in rare cases, such pain may also be linked to prostate cancer. It is important to pay attention to other symptoms that could indicate something more serious. For example, if you experience persistent pain that does not go away, difficulty or pain when urinating (dysuria), blood in your urine or semen, or unexpected weight loss, it might be a sign that you should get checked by a doctor. Your healthcare provider may perform a physical exam, ask about your symptoms, and order tests such as blood work or imaging studies to make a proper diagnosis. Although perineal pain alone is rarely a clear sign of cancer, association with other symptoms could suggest a need for further evaluation. Early detection of any serious condition, including prostate cancer, can help ensure that you receive the appropriate treatment.
(References)
Giles LG. Perineal discomfort in prostatic adenocarcinoma. JRSM Short Rep. 2010 Oct 1;1(5):38. doi: 10.1258/shorts.2010.010047. PMID: 21103130; PMCID: PMC2984366.
Mehta P, Leslie SW, Reddivari AKR. Dysuria. [Updated 2023 Nov 12]. In: StatPearls [Internet].
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