Can Persistent Tiredness Lead to Feelings of Depression, and What Role Does Testosterone Play in This?

When someone feels tired every day, it can make their life feel harder and make them feel low or sad. Tiredness can change how a person sees themselves and the world around them. This long-term tiredness might lead to feelings of depression because the body and brain are not getting enough rest and energy to feel happy. Testosterone is a hormone that helps many parts of the body work well, including the brain and muscles. In men, low testosterone levels have been linked to more tiredness and sometimes a lower mood. Research has found that giving testosterone to men who do not have enough of it can sometimes help reduce fatigue and improve energy. However, some studies have also shown that testosterone therapy is connected to problems like depression and even thoughts of self-harm. This means that while testosterone is important for feeling energetic and happy, it does not work the same way for everyone. If someone is feeling very tired and sad often, it is important for them to talk to a healthcare provider to understand all the factors, including hormone levels, that might be affecting their mood.