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Published on: 2/1/2026

Pregnancy and STIs: Critical Risks and Screening Protocols for New Moms

Pregnancy and STIs: early detection and treatment protect both parent and baby; risks of untreated infections include preterm birth, low birth weight, newborn infections, and even miscarriage or stillbirth, so routine screening at the first prenatal visit for syphilis, HIV, hepatitis B, chlamydia, and gonorrhea, with repeat testing in the third trimester based on risk, is essential. There are several factors to consider, including that many STIs are silent, partners may need testing, some viral infections are managed rather than cured, and certain symptoms require urgent care. See below for full screening protocols, warning signs, and the next steps to take with your provider.

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Explanation

Pregnancy and STIs: Critical Risks and Screening Protocols for New Moms

Pregnancy is a time of major physical and emotional change. Along with routine prenatal care, understanding sexually transmitted infections (STIs) is an important part of protecting both the pregnant person and the baby. STIs are common, often treatable, and—when identified early—much less likely to cause harm. This guide explains key risks, STI symptoms, and recommended screening protocols using information supported by trusted medical authorities such as the CDC, WHO, and the American College of Obstetricians and Gynecologists (ACOG).

The goal is not to cause fear, but to support informed, practical decisions that keep families healthy.


Why STIs Matter During Pregnancy

STIs can affect pregnancy in different ways depending on the infection, the timing of exposure, and whether treatment is received. Some infections can be passed from parent to baby during pregnancy, labor, or delivery. Others can increase the risk of pregnancy complications.

Potential risks of untreated STIs during pregnancy include:

  • Preterm birth or low birth weight
  • Miscarriage or stillbirth
  • Infection of the uterus or placenta
  • Newborn infections affecting the eyes, lungs, brain, or blood
  • Long-term health issues for the baby, such as hearing or vision loss

The good news is that most of these outcomes are preventable with proper screening and timely treatment.


Understanding STI Symptoms in Pregnancy

One challenge with STIs is that many cause mild or no symptoms at all, especially in women. Pregnancy can also mask or mimic STI symptoms, making them harder to recognize.

Common STI symptoms to be aware of include:

  • Unusual vaginal discharge (color, odor, or texture changes)
  • Burning or pain during urination
  • Genital itching, sores, blisters, or rashes
  • Pelvic or lower abdominal pain
  • Bleeding between periods or after sex
  • Pain during sex

During pregnancy, symptoms like discharge or pelvic discomfort may be dismissed as "normal." While many changes are normal, it's important not to assume. Any new, worsening, or unusual symptom should be discussed with a healthcare provider.


Common STIs of Concern During Pregnancy

Chlamydia

  • Often has no symptoms
  • Can cause preterm birth and eye or lung infections in newborns
  • Easily treated with pregnancy-safe antibiotics

Gonorrhea

  • May cause discharge or pelvic pain, but often silent
  • Can lead to serious eye infections or bloodstream infections in newborns
  • Treatment during pregnancy is effective and recommended

Syphilis

  • May begin with a painless sore, then rash or flu-like symptoms
  • Can cause miscarriage, stillbirth, or severe congenital infection
  • Early screening and treatment are critical

HIV

  • May cause no early symptoms
  • Can be passed to the baby during pregnancy, birth, or breastfeeding
  • Modern treatment dramatically reduces transmission risk

Hepatitis B

  • Often asymptomatic
  • Can be transmitted at birth
  • Newborn vaccination and maternal screening prevent complications

Herpes (HSV)

  • Causes blisters or sores, but many people have no symptoms
  • Risk to baby is highest with a new infection late in pregnancy
  • Antiviral management and delivery planning reduce risk

STI Screening Protocols for Pregnant Patients

Medical organizations recommend routine STI screening as part of prenatal care, even when no symptoms are present. Screening is about prevention—not judgment.

Typical screening includes:

At the First Prenatal Visit

  • Chlamydia and gonorrhea (especially under age 25 or at increased risk)
  • Syphilis (for all pregnant patients)
  • HIV (for all pregnant patients)
  • Hepatitis B

During the Third Trimester

Repeat testing may be recommended if:

  • There is a new or multiple sexual partner
  • There is a history of STIs
  • There are ongoing risk factors
  • Initial testing was positive earlier in pregnancy

At Delivery

  • Additional testing may occur if prior screening was incomplete or risk factors emerged late in pregnancy.

These protocols are based on strong evidence showing that early detection saves lives.


Treatment: What New Moms Should Know

Most bacterial STIs can be safely treated during pregnancy. Treatment decisions are carefully chosen to protect fetal development.

Key points:

  • Do not delay treatment if an STI is diagnosed
  • Always complete the full course of prescribed medication
  • Sexual partners often need testing and treatment to prevent reinfection
  • Follow-up testing may be required to confirm cure

Viral STIs (such as HIV or herpes) are managed rather than cured, but modern therapies significantly reduce health risks for both parent and baby.


Emotional Health, Consent, and Sexual Trauma

STI care isn't only physical—it can bring up emotional or psychological concerns, especially for those with past experiences of sexual trauma. Pregnancy can resurface difficult feelings related to bodily autonomy, exams, or testing.

If you're experiencing emotional distress or wondering whether past experiences may be affecting your current health, a free AI-powered sexual trauma symptom checker can help you understand what you're going through and guide you toward supportive resources.

Healthcare providers can adapt care approaches when they understand a patient's history, helping exams and discussions feel safer and more respectful.


Reducing Risk During and After Pregnancy

While not all STIs are preventable, risk can be reduced with informed choices:

  • Use condoms consistently if there is any risk of exposure
  • Attend all prenatal appointments and recommended screenings
  • Encourage partners to get tested when appropriate
  • Avoid assuming absence of STI symptoms means absence of infection
  • Communicate openly with healthcare providers

After birth, postpartum visits are also an opportunity to revisit sexual health, contraception, and STI prevention.


When to Speak to a Doctor Right Away

Some symptoms or situations need prompt medical attention, especially during pregnancy:

  • Severe pelvic or abdominal pain
  • Fever with genital symptoms
  • Painful sores or rapidly spreading rash
  • Sudden bleeding
  • Known exposure to an STI

If anything feels serious, worsening, or life‑threatening, speak to a doctor immediately or seek urgent medical care. Trust your instincts—early evaluation can make a critical difference.


The Bottom Line for New Moms

STIs are common, manageable, and often silent. Understanding STI symptoms, following screening protocols, and seeking timely care are powerful steps in protecting both maternal and infant health. Pregnancy is not a time for blame or fear—it's a time for proactive, compassionate healthcare.

If you have concerns, questions, or symptoms, speak to a doctor. Open, honest conversations and evidence‑based screening save lives and support healthy beginnings for families.

(References)

  • * ACOG Practice Bulletin No. 221: Screening for Sexually Transmitted Infections in Pregnancy. Obstet Gynecol. 2020 May;135(5):e162-e179. doi: 10.1097/AOG.0000000000003813. PMID: 32330736.

  • * Park C, et al. Maternal and congenital syphilis: The global landscape and the way forward. PLoS Med. 2021 Jul 27;18(7):e1003711. doi: 10.1371/journal.pmed.1003711. PMID: 34310574; PMCID: PMC8315127.

  • * Ratanasirichat N, Teeraananchai S, Kongwattanakul K. Sexually Transmitted Infections in Pregnant Women: A Review of Current Treatment and Management Strategies. Infect Dis Obstet Gynecol. 2020 Jul 15;2020:6463935. doi: 10.1155/2020/6463935. PMID: 32733158; PMCID: PMC7378393.

  • * Money D, Steben M; Society of Obstetricians and Gynaecologists of Canada (SOGC) Infectious Diseases Committee. Herpes simplex virus and pregnancy. J Obstet Gynaecol Can. 2020 Dec;42(12):1567-1574. English, French. doi: 10.1016/j.jogc.2020.08.005. PMID: 33261775.

  • * Chou R, et al. HIV Screening in Pregnant Women: A Review of the Evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2019 Jun 4;170(11):775-783. doi: 10.7326/M18-3011. PMID: 31160822.

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