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Published on: 8/20/2026

How is pus in the urine diagnosed?

Pyuria, or pus in the urine, is diagnosed through a urinalysis. A urine sample is examined under a microscope to detect the presence of white blood cells (WBCs), which indicate infection or inflammation in the urinary tract. Generally, more than 10 WBCs per cubic millimeter of urine confirms pyuria. Additional tests, such as a urine culture, may be ordered to identify the underlying cause.

Because pyuria can signal a range of conditions—from urinary tract infections to kidney issues or other systemic problems—understanding your symptoms early is key to getting the right care. Take a free, instant, online symptom check to better understand what may be causing your symptoms and confidently navigate your next steps.

Reviewed for medical accuracy: 07/15/2026

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Explanation

Pyuria is the presence of pus in the urine, which indicates white blood cells are present. This condition is often diagnosed by taking a urine sample and examining it under a microscope. The presence of white blood cells, or leukocytes, in the urine is a key indicator of pyuria.

Diagnosis Steps:

  1. Urine Sample Collection: A clean-catch urine sample is typically collected to avoid contamination.
  2. Microscopic Examination: The urine is examined under a microscope to look for white blood cells. A high number of these cells suggests pyuria.
  3. Chemical Tests: Sometimes, chemical tests are also used to detect leukocyte esterase, an enzyme found in white blood cells, which further confirms pyuria.

Pyuria can be a sign of a urinary tract infection (UTI) or other medical conditions. If you're experiencing urinary symptoms, you can use a free symptom checker to help identify potential causes before consulting with a healthcare provider for further evaluation and treatment.

(References)

  • Thyagaraju P, Mandal J, Pari Thenmozhi H, & Deepanjali S. (2024). Pyuria in hospitalized general medical patients without .... F1000Research, 39346951.

  • Rahman AJ, Naz F, & Ashraf S. (2011). Significance of pyuria in the diagnosis of urinary tract .... JPMA. The Journal of the Pakistan Medical Association, 22368908.

  • Ditchburn RK, & Ditchburn JS. (1990). A study of microscopical and chemical tests for the rapid .... The British journal of general practice : the journal of the Royal College of General Practitioners, 2271260.

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