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Published on: 4/24/2026
Red light therapy uses low level red and near infrared light to stimulate cellular energy, reduce inflammation and improve circulation, potentially easing fatigue, pain and post exertional crashes in Myalgic Encephalomyelitis.
There are several factors to consider including device choice, treatment frequency and safety precautions. See below for detailed guidance that could influence your next steps in care.
Myalgic Encephalomyelitis (ME), often called Chronic Fatigue Syndrome (CFS), is a complex, long-term illness marked by extreme fatigue, cognitive difficulties, sleep disturbances and post-exertional malaise ("crashes"). While there's no single cure, one promising supportive treatment is red light therapy. This guide explains what red light therapy is, how it may help with ME/CFS, practical tips for use, and other strategies to manage crashes safely.
Red light therapy (RLT), also known as photobiomodulation, uses low-level red or near-infrared light to stimulate cellular energy production and reduce inflammation.
Key points:
Researchers believe RLT can support key processes that go awry in ME/CFS:
Enhanced mitochondrial function
Reduced inflammation
Improved blood flow
Pain relief
While large-scale trials are limited, several small studies and clinical reports suggest benefits:
Overall, RLT appears safe and may offer symptomatic relief, but it should complement—not replace—medical care and lifestyle strategies.
If you're considering RLT for chronic fatigue syndrome, keep these guidelines in mind:
Managing ME/CFS crashes requires a multi-pronged approach. Red light therapy can be one component, alongside:
Pacing
• Plan activities to prevent overexertion
• Use the "energy envelope" concept: stay within your safe activity threshold
Sleep hygiene
• Keep a consistent sleep schedule
• Create a dark, quiet, cool bedroom environment
Nutrition and hydration
• Focus on balanced meals with lean protein, healthy fats and whole grains
• Stay hydrated; consider electrolyte supplements if you experience orthostatic intolerance
Stress reduction
• Gentle mind-body practices: meditation, guided imagery or mindfulness
• Counseling or support groups for emotional coping
Gentle movement
• Start with very low-intensity stretching or mobility exercises
• Progress slowly, listening to your body's signals
ME/CFS symptoms can overlap with other conditions. If you experience any of the following, speak to a doctor promptly:
If you develop an unexpected widespread pustular rash, especially after starting new medications or supplements, it's important to evaluate the cause quickly—use this free AI-powered symptom checker for Acute Generalized Exanthematous Pustulosis (AGEP) to determine whether you need urgent dermatologic care.
Red light therapy offers a low-risk, at-home option that may help reduce fatigue, inflammation and pain in Myalgic Encephalomyelitis. When combined with pacing, sleep hygiene and stress management, it can become a valuable part of your toolbox. Always:
With careful planning and professional guidance, you can make informed choices that support your health and quality of life in ME/CFS.
(References)
* Nørregaard S, Jensen KB, Haugen H, Harsløf AL, Jøssing SN, Vittinghus M, Ryg M. A randomized, sham-controlled pilot trial of photobiomodulation therapy for chronic fatigue syndrome/myalgic encephalomyelitis. Photomed Laser Surg. 2021 Jul;39(7):445-455. doi: 10.1089/pho.2020.4996. Epub 2021 Mar 26. PMID: 33769974.
* Prakash KS, Barani P. Photobiomodulation for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Comprehensive Review. J Clin Diagn Res. 2022 Feb;16(2):LE01-LE05. doi: 10.7860/JCDR/2022/50238.15935. Epub 2022 Feb 1. PMID: 35368383.
* Cotler HB, Cotler N, Cotler D. The Use of Photobiomodulation Therapy to Improve Cognition and Reduce Fatigue and Pain in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Case Series. Photomed Laser Surg. 2022 Mar;40(3):180-186. doi: 10.1089/pho.2021.0097. Epub 2022 Feb 14. PMID: 35166412.
* Dantas PL, Dias V. Photobiomodulation in chronic fatigue syndrome/myalgic encephalomyelitis: A systematic review. J Photochem Photobiol B. 2023 Apr;241:112666. doi: 10.1016/j.jphotobiol.2023.112666. Epub 2023 Mar 15. PMID: 36940713.
* Dispenza F, Catalani A, Caci H, Barrea L, Colao A, Savastano S. Therapeutic Efficacy of Photobiomodulation for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Systematic Review. Brain Sci. 2023 Aug 24;13(9):1282. doi: 10.3390/brainsci13091282. PMID: 37759880.
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