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Published on: 5/6/2025

Why Is My Right Lower Abdomen Swollen?

Swelling in your right lower abdomen can be due to inflammation from conditions like appendicitis, enlarged lymph nodes from infection or inflammation, colitis, ovarian cyst or rupture, constipation, or even generalized abdominal bloating that may appear more pronounced in that area.

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Explanation

There are several reasons you might notice swelling in the right lower part of your abdomen:

  • Acute Inflammatory Processes (e.g., Appendicitis): If the appendix becomes inflamed, it can cause localized swelling in the right lower quadrant. This is a common cause of acute abdominal swelling and pain.

  • Enlarged Mesenteric Lymph Nodes: Sometimes, infections or inflammatory conditions lead to the enlargement of the mesenteric lymph nodes. These nodes, which are part of your immune response in the gut, can become noticeable on imaging studies and might contribute to a feeling of swelling in that area.

  • Abdominal Bloating: Bloating is another frequent cause of apparent abdominal swelling. Dietary changes may lead to gas buildup which can sometimes be more noticeable in the right lower abdomen. Even constipation which can cause stool build up may result in swelling in one part of your abdomen.

  • Acute Inflammatory Processes (e.g., appendicitis, colitis):

      If the appendix becomes inflamed, it can cause localized swelling in the right lower quadrant. This is a common cause of acute abdominal swelling and pain.  Colitis which is an inflammation or infection of the colon, can also result in pain or swelling in the abdomen. 
    
  • Enlarged Mesenteric Lymph Nodes: Sometimes, infections or inflammatory conditions lead to the enlargement of the mesenteric lymph nodes. These nodes, which are part of your immune response in the gut, can become noticeable on imaging studies and might contribute to a feeling of swelling in that area.

  • Ovarian cyst with rupture: This may result in pain and swelling on one side of the abdomen. In the case of ovarian torsion, this would be a medical emergency.

Since these causes range from transient issues like bloating to more serious conditions such as appendicitis, it's important to have any persistent or concerning swelling be evaluated by a healthcare provider. They can perform a physical examination and recommend appropriate imaging studies (like an ultrasound or CT scan) to determine the exact cause and suggest the right treatment.

(References)

  • Wonski S, Ranzenberger LR, Carter KR. Appendix Imaging. 2023 Apr 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31751093.

  • Lucey BC, Stuhlfaut JW, Soto JA. Mesenteric lymph nodes seen at imaging: causes and significance. Radiographics. 2005 Mar-Apr;25(2):351-65. doi: 10.1148/rg.252045108. PMID: 15798054.

  • Shacker M, Latorre-Rodríguez AR, Mittal SK. Prevalence and severity of abdominal bloating in patients with gastroesophageal reflux disease. Dis Esophagus. 2024 Jan 31;37(2):doad058. doi: 10.1093/dote/doad058. PMID: 37738150.

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