What could cause severe lightheadedness when standing in someone with multiple myeloma?

Lightheadedness when standing up can be a sign of orthostatic hypotension, especially in someone with multiple myeloma. This condition happens when blood pressure drops too much when a person stands up, which can make them feel dizzy or faint.

Possible Causes:

• Delayed Orthostatic Hypotension: This is when the body's response to standing is slower, leading to dizziness or lightheadedness after a delay. It can be related to issues with blood vessels or nerves that control blood pressure (Reference 1).
• Neurogenic Factors: Sometimes, the nerves that help control blood pressure don't work properly. This can cause the blood pressure to drop when standing, which is common in people with certain blood conditions (Reference 2).

What Can Be Done:

• Monitoring and Management: It's important to keep an eye on blood pressure changes and manage them with the help of healthcare providers. They can offer treatments or lifestyle changes to help manage symptoms (Reference 3).

If you or someone you know experiences these symptoms, it's important to talk to a healthcare provider for proper evaluation and management.