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Published on: 5/6/2025

What Are the Possible Reasons for Side Knee Pain?

Side knee pain can come from issues with the iliotibial band, soft tissue injuries around the knee, or even problems linked to knee surgery.

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Explanation

There are several possible reasons for pain on the side of your knee. One common cause is iliotibial (IT) band syndrome. The IT band is a thick band of tissue that runs along the outside of your thigh to your knee. When it gets tight or overused, it can rub against the knee and cause pain. Another reason can be soft tissue injuries. This may happen when muscles, tendons, or other tissues on the side of the knee are strained from activities like running or sports. In some cases, people who have had knee surgery, like total knee arthroplasty, can experience isolated lateral knee pain. This pain might occur because of changes in joint alignment or the way the soft tissue moves around the new joint. Sometimes, other imbalances or stress in the knee area can also lead to pain on the side. All these issues can make everyday activities uncomfortable, and it is important to check with a doctor if the pain continues or worsens.

(References)

  • Khaund R, Flynn SH. Iliotibial band syndrome: a common source of knee pain. Am Fam Physician. 2005 Apr 15;71(8):1545-50. PMID: 15864895

  • Winslow J. Treatment of lateral knee pain using soft tissue mobilization in four female triathletes. Int J Ther Massage Bodywork. 2014 Sep 3;7(3):25-31. PMID: 25184012; PMCID: PMC4145001.

  • Cheppalli NS, Purudappa PP, Price R, Kolwadkar Y, Metikala S. Isolated lateral-sided knee pain in total knee arthroplasty. A review. Orthop Rev (Pavia). 2024 Mar 17;16:93014. doi: 10.52965/001c.93014. PMID: 38505137; PMCID: PMC10950199.

  • English S, Perret D. Posterior knee pain. Curr Rev Musculoskelet Med. 2010 Jun 12;3(1-4):3-10. doi: 10.1007/s12178-010-9057-4. PMID: 21063493; PMCID: PMC2941578.

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