Doctors Note Logo

Back

Published on: 4/28/2025

What Could Cause Whole Body Numbness and Tingling Simultaneously?

Whole body numbness and tingling can happen for several reasons, such as nerve damage from systemic diseases like diabetes, liver cirrhosis, autoimmune conditions like Behçet's disease or Sneddon’s syndrome, and even stroke-related issues.

answer background

Explanation

When you feel numbness and tingling all over your body, it means your nerves are sending mixed-up signals. One reason for this is peripheral neuropathy, which can be seen in people with diabetes and liver cirrhosis. In cirrhosis, the liver’s problems may affect the blood and chemicals that help nerves work correctly. Some autoimmune conditions, like Behçet's disease, can also cause nerve problems, making you feel numb and tingly. Another possible cause is Sneddon’s syndrome, a rare condition where blood flow and small blood vessels are affected, sometimes leading to widespread neuropathic pain. In other cases, a stroke—especially in areas like the pons in the brain—might lead to unusual sensations. Although strokes usually affect one side of the body, they can sometimes cause mixed sensations that seem to spread. If you experience whole body numbness and tingling, especially if it comes on suddenly or is accompanied by other symptoms like weakness or confusion, it is important to talk with a healthcare provider who can check your nerves and overall health.

(References)

  • Kharbanda PS, Prabhakar S, Chawla YK, Das CP, Syal P. Peripheral neuropathy in liver cirrhosis. J Gastroenterol Hepatol. 2003 Aug;18(8):922-6. doi: 10.1046/j.1440-1746.2003.03023.x. PMID: 12859721.

  • Borhani-Haghighi A, Samangooie S, Ashjazadeh N, Nikseresht A, Shariat A, Yousefipour G, Safari A. Neurological manifestations of Behçet's disease. Saudi Med J. 2006 Oct;27(10):1542-6. PMID: 17013480.

  • Brigo F, Tomelleri G, Bovi P, Bovi T. Hemiparesthesias in lacunar pontine ischemic stroke. Neurol Sci. 2012 Jun;33(3):619-21. doi: 10.1007/s10072-011-0773-3. Epub 2011 Sep 11. PMID: 21910003.

  • Dag E, Gokce B, Kocak M. Sneddon's syndrome presenting with neuropathic pain. Skinmed. 2013 Jul-Aug;11(4):251-2. PMID: 24053013.

Tell your friends about us.

We would love to help them too.

smily Shiba-inu looking

For First Time Users

What is Ubie’s Doctor’s Note?

We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.

Learn more about symptoms

Pins and needles all over my body

Not sure about the cause of your current symptoms?

AI Symptom Check

Try our AI-based symptom checker

With an easy 3-min questionnaire, you can get a free AI-powered report on possible causes


Tips to try:

  • Provide specific, detailed info about all symptoms you have.
  • Give accurate information about yourself including current conditions.
  • Answer all follow-up questions

Purpose and positioning of servicesUbie Doctor’s Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.