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Published on: 2/28/2026
Calcium carbonate neutralizes stomach acid on contact, giving fast relief for occasional heartburn and mild stomach burning when used as directed.
If symptoms occur more than twice weekly, wake you at night, or include trouble swallowing, vomiting, weight loss, chest pain, or black stools, medically approved next steps may include H2 blockers or PPIs, H. pylori testing, and lifestyle changes. There are several factors to consider, including pregnancy, kidney disease, and drug interactions; see the complete guidance below to choose the safest next steps.
A burning feeling in your stomach or chest can be uncomfortable and distracting. For many people, it happens after eating, when lying down, or during times of stress. One of the most common and trusted treatments is calcium carbonate—a widely used antacid found in many over‑the‑counter products.
But why does calcium carbonate work? And when is it enough—and when should you do more?
Let's break it down clearly and medically.
That burning sensation is usually caused by stomach acid irritating the lining of your stomach or esophagus. Common reasons include:
Your stomach normally produces acid to digest food. Problems occur when:
That's where calcium carbonate comes in.
Calcium carbonate is an antacid. It works by neutralizing stomach acid on contact.
Here's how it helps:
Because it works directly on stomach acid, calcium carbonate provides fast relief, often within minutes.
It is commonly recommended by healthcare professionals for occasional heartburn and mild indigestion.
Calcium carbonate is best for:
If your symptoms happen once in a while, especially after large meals or certain trigger foods, calcium carbonate is often enough.
Even though calcium carbonate is available over the counter, it should still be used properly.
Most people tolerate calcium carbonate well. However, side effects can include:
Taking high doses regularly can lead to:
This is why it's important not to treat frequent symptoms with antacids alone without medical guidance.
If your stomach burning:
—it may signal a more serious issue.
Conditions such as GERD, gastritis, ulcers, or even more serious digestive disorders require evaluation beyond simple antacids.
If you're experiencing persistent stomach burning and suspect inflammation of your stomach lining might be the culprit, you can use Ubie's free AI-powered Gastritis symptom checker to get personalized insights about your symptoms and understand whether you should seek medical care.
This type of tool can help you decide whether it's time to see a healthcare provider.
If symptoms persist, doctors may recommend other treatments based on the cause.
Examples include famotidine.
They reduce acid production and last longer than calcium carbonate.
Examples include omeprazole.
They significantly reduce acid production and are often used for:
These should be used under medical guidance, especially long-term.
If gastritis or ulcers are suspected, your doctor may test for Helicobacter pylori, a common bacterial infection that irritates the stomach lining.
Often overlooked, these changes can be just as important as medication:
These steps reduce acid irritation at the source.
Most cases are mild. However, seek immediate medical care if you experience:
These could indicate bleeding ulcers, heart problems, or other serious conditions.
Do not ignore these warning signs.
Calcium carbonate is commonly used during pregnancy for heartburn and is generally considered safe in recommended doses. Still, speak to your doctor before regular use.
Excess calcium can be dangerous. Always consult your healthcare provider before using calcium carbonate frequently.
Calcium carbonate can interfere with absorption of:
Separate doses by at least 2 hours unless instructed otherwise.
Calcium carbonate works because it directly neutralizes stomach acid, offering fast and effective relief for occasional stomach burning and heartburn.
For mild, infrequent symptoms, it's a trusted and medically supported option.
However:
If your symptoms are ongoing, worsening, or accompanied by other concerning signs, take the next step. Consider checking your symptoms using Ubie's free AI-powered Gastritis tool to better understand what might be happening, and most importantly, speak to a doctor to rule out anything serious or potentially life-threatening.
Stomach burning is common—but it shouldn't control your life. The right combination of proper diagnosis, appropriate medication, and lifestyle changes can bring lasting relief.
(References)
* El-Serag HB, et al. Pharmacologic treatment of gastroesophageal reflux disease (GERD): what has worked, what has not, and what is next. Gastroenterol Clin North Am. 2019 Sep;48(3):475-487. doi: 10.1016/j.gtc.2019.05.002. Epub 2019 Jun 21. PMID: 31395221.
* Konda V, et al. AGA Clinical Practice Update on the First-Line Treatment for Gastroesophageal Reflux Disease: Expert Review. Clin Gastroenterol Hepatol. 2022 Mar;20(3):477-483.e1. doi: 10.1016/j.cgh.2021.11.025. Epub 2021 Nov 25. PMID: 34840134.
* Daghman A, et al. Pharmacotherapy for gastroesophageal reflux disease: a critical appraisal. Expert Opin Pharmacother. 2021 Jan;22(1):47-59. doi: 10.1080/14656566.2020.1802928. Epub 2020 Aug 17. PMID: 32777821.
* Newberry C, et al. Diet and lifestyle changes for gastroesophageal reflux disease. Curr Opin Gastroenterol. 2020 Mar;36(2):120-125. doi: 10.1097/MOG.0000000000000624. PMID: 31923050.
* Kahan SM, et al. Approach to the Patient with Dyspepsia and Heartburn. Med Clin North Am. 2021 May;105(3):453-470. doi: 10.1016/j.mcna.2021.01.002. Epub 2021 Feb 20. PMID: 33896574.
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