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Published on: 2/23/2026

Stomach Burning? Why H. Pylori Is the Cause & Medically Approved Next Steps

Persistent stomach burning is often caused by H. pylori, a common bacterial infection that irritates the stomach lining and can lead to ulcers; it is confirmed with a urea breath or stool antigen test and treated with combination antibiotics plus an acid reducer such as a PPI. There are several factors to consider, including when to test, how to take the medicines correctly, and red flags like vomiting blood, black stools, or severe pain that require urgent care; see below for complete, medically approved next steps that could change what you do next.

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Explanation

Stomach Burning? Why H. Pylori May Be the Cause & Medically Approved Next Steps

A burning feeling in your stomach can be uncomfortable, distracting, and sometimes worrying. While occasional stomach irritation can happen after spicy food or stress, ongoing or repeated burning may point to something more specific. One of the most common medical causes is h pylori (Helicobacter pylori) — a bacterial infection that affects the stomach lining.

Understanding what h pylori is, how it causes symptoms, and what to do next can help you take the right steps toward relief.


What Is H. Pylori?

H pylori is a type of bacteria that infects the stomach. It is extremely common worldwide. In fact, many people have h pylori and don't even realize it.

This bacterium survives in the acidic environment of the stomach by producing substances that weaken the protective lining. Over time, this can lead to:

  • Stomach inflammation (gastritis)
  • Burning stomach pain
  • Peptic ulcers
  • In rare cases, stomach cancer

Not everyone with h pylori develops symptoms. But when symptoms appear, stomach burning is one of the most frequent complaints.


Why Does H. Pylori Cause Burning?

Your stomach normally has a protective mucus layer that shields it from strong digestive acid. H pylori damages this protective barrier.

As a result:

  • Stomach acid can irritate the sensitive lining
  • Inflammation develops
  • Small sores (ulcers) may form
  • You may feel burning or gnawing pain

The discomfort is often described as:

  • A burning sensation in the upper abdomen
  • Pain that may improve or worsen after eating
  • Bloating or fullness
  • Nausea
  • Frequent burping

If left untreated, inflammation caused by h pylori can persist for years.


Common Symptoms of H. Pylori Infection

Not everyone has symptoms, but when they do occur, they may include:

  • Burning or aching stomach pain
  • Pain that worsens on an empty stomach
  • Bloating
  • Nausea
  • Loss of appetite
  • Frequent burping
  • Mild, unexplained weight loss

Seek urgent medical care if you notice:

  • Vomiting blood
  • Black or tarry stools
  • Severe abdominal pain
  • Difficulty swallowing
  • Persistent vomiting

These symptoms may indicate bleeding ulcers or other serious complications and require immediate medical attention.


How Do You Get H. Pylori?

H pylori spreads through:

  • Contaminated food or water
  • Close contact with infected saliva
  • Poor sanitation conditions

Many people acquire the infection in childhood. It can remain silent for years before causing symptoms.

Importantly, having h pylori does not mean you did anything wrong. It is one of the most common infections globally.


How Is H. Pylori Diagnosed?

If your doctor suspects h pylori, they may recommend:

Non-invasive tests:

  • Urea breath test
  • Stool antigen test
  • Blood antibody test (less commonly used today)

In some cases:

  • Upper endoscopy with biopsy

Breath and stool tests are the most accurate for confirming an active infection.

If you're experiencing burning stomach pain and want to better understand whether your symptoms align with Gastritis, you can use a free AI-powered symptom checker to evaluate your symptoms and determine if you should seek medical attention.


Medically Approved Treatment for H. Pylori

The good news is that h pylori is treatable.

Treatment typically includes:

1. Combination Antibiotic Therapy

Doctors usually prescribe:

  • Two different antibiotics
  • Taken for 10–14 days

Using two antibiotics helps prevent resistance and improves cure rates.

2. Acid-Reducing Medication

  • Proton pump inhibitors (PPIs) such as omeprazole
  • These reduce stomach acid and allow healing

3. Sometimes Bismuth Medication

  • Helps protect the stomach lining
  • May be included in certain treatment regimens

It's important to take all medications exactly as prescribed — even if you start feeling better quickly. Stopping early can lead to antibiotic resistance and incomplete treatment.


What Happens If H. Pylori Is Not Treated?

Untreated h pylori infection can lead to:

  • Chronic gastritis
  • Peptic ulcers
  • Bleeding ulcers
  • Iron deficiency anemia
  • Increased risk of stomach cancer (over many years)

While the risk of serious complications is real, most people who receive proper treatment recover fully.

The key is early diagnosis and appropriate therapy.


Lifestyle Changes That May Help

While antibiotics are necessary to eliminate h pylori, certain habits may reduce irritation and support healing:

  • Avoid NSAIDs (like ibuprofen) unless advised by your doctor
  • Limit alcohol
  • Stop smoking
  • Reduce very spicy or acidic foods if they worsen symptoms
  • Eat smaller, more frequent meals

Diet alone cannot cure h pylori, but it can help manage discomfort during treatment.


When Should You See a Doctor?

You should speak to a doctor if:

  • Stomach burning lasts more than a few days
  • Pain keeps coming back
  • Over-the-counter acid reducers don't help
  • You have unexplained weight loss
  • You notice signs of bleeding

If anything feels severe, unusual, or life-threatening, seek immediate medical care.

Persistent stomach burning should not be ignored. While many causes are mild, h pylori and ulcers require proper medical evaluation.


Can H. Pylori Come Back?

Reinfection is possible but uncommon in adults after successful treatment.

Your doctor may recommend repeat testing (usually a breath or stool test) several weeks after treatment to confirm the infection is gone.

If symptoms return later, further evaluation may be necessary.


The Bottom Line

Stomach burning is common, but when it persists, h pylori is one of the most important causes to rule out.

Here's what you should remember:

  • H pylori is a common bacterial infection of the stomach.
  • It can cause burning pain, gastritis, and ulcers.
  • Diagnosis is simple with breath or stool testing.
  • Treatment requires antibiotics plus acid-reducing medication.
  • Early treatment prevents complications.

Most importantly, don't self-diagnose or self-treat ongoing stomach pain. While online information can guide you, a medical professional should confirm the diagnosis and recommend the right therapy.

If you are experiencing persistent stomach burning, worsening symptoms, vomiting blood, black stools, or severe pain, speak to a doctor immediately. Some complications of h pylori infection can be serious and even life-threatening if left untreated.

Taking action early is the safest and most effective way to protect your stomach health.

(References)

  • * Chey WD, Leontiadis DI, Howden CW, Moss SF. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol. 2017 Aug;112(8):1228-1253. doi: 10.1038/ajg.2017.139. PMID: 28671695.

  • * Malfertheiner P, Megraud F, O'Morain FJ, Gisbert JP, Kuipers EJ, Axon AJ, Bazzoli F, Gasbarrini A, Atherton J, Graham DY, Hunt R, Moayyedi P, Rokkas N, Vakil N, Xiang Z. Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report. Gut. 2017 Jan;66(1):6-30. doi: 10.1136/gutjnl-2016-312214. Epub 2016 Oct 5. PMID: 27530033.

  • * Ford AC, Qumseya BJ, Lindberg G, Chey WD, van Zanten SV, Leontiadis GI. Effect of eradication of Helicobacter pylori on dyspeptic symptoms. JAMA. 2014 Feb 19;311(7):723-30. doi: 10.1001/jama.2014.197. PMID: 24549292.

  • * Gisbert JP, Castiella A. Update on Helicobacter pylori diagnosis and management. Curr Opin Gastroenterol. 2021 Nov 1;37(6):531-539. doi: 10.1097/MOG.0000000000000778. PMID: 34506381.

  • * Talley NJ, Walker MM, Murray JA, Koloski NA, Saito YA. Functional dyspepsia. Lancet. 2021 Dec 4;398(10316):2025-2035. doi: 10.1016/S0140-6736(21)00672-X. Epub 2021 Aug 17. PMID: 34416174.

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