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Published on: 5/15/2025

What Might Cause a Sudden Inability to Walk Straight?

A sudden inability to walk straight can stem from problems with balance or muscle control, possibly due to conditions affecting the brain or other body systems.

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Explanation

Difficulty walking straight may indicate a problem in the brain's control centers. This includes issues with the basal ganglia, which control movement patterns, and the cerebellum, which coordinates balance and precise movements. Other potential causes include stroke, multiple sclerosis, or medications that affect brain function. Balance problems can also arise from inner ear dysfunction or blood pressure changes, leading to dizziness or unsteadiness. Muscle weakness or nerve conditions affecting leg control can impair walking. For example, nerve disorders like peripheral neuropathy can reduce foot sensation, making it difficult to sense the ground properly. A sudden change in walking ability should be evaluated promptly by a healthcare provider to determine the specific cause and appropriate treatment.

(References)

  • Nutt JG, Bloem BR, Giladi N, Hallett M, Horak FB, Nieuwboer A. Freezing of gait: moving forward on a mysterious clinical phenomenon. Lancet Neurol. 2011 Aug;10(8):734-44. doi: 10.1016/S1474-4422(11)70143-0. PMID: 21777828; PMCID: PMC7293393.

  • Raccagni C, Nonnekes J, Bloem BR, Peball M, Boehme C, Seppi K, Wenning GK. Gait and postural disorders in parkinsonism: a clinical approach. J Neurol. 2020 Nov;267(11):3169-3176. doi: 10.1007/s00415-019-09382-1. Epub 2019 May 22. PMID: 31119450; PMCID: PMC7578144.

  • Ashizawa T, Xia G. Ataxia. Continuum (Minneap Minn). 2016 Aug;22(4 Movement Disorders):1208-26. doi: 10.1212/CON.0000000000000362. PMID: 27495205; PMCID: PMC5567218.

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