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Published on: 1/30/2026
Get the Tdap vaccine during every pregnancy at 27 to 36 weeks, ideally earlier in that window, so your antibodies cross the placenta and help protect your newborn from whooping cough before their own shots begin. The vaccine is well studied and safe, and there are several factors to consider including what to do if you missed it, expected side effects, and making sure close contacts are protected, so see below for important details that may affect your next steps.
Pregnancy is a time filled with important choices, and many of them are about protecting not just your own health, but your baby’s too. One of the most important—and often misunderstood—decisions is when to get the Tdap vaccine during pregnancy. Understanding the timing and the reason behind it can help you feel confident and prepared.
This article explains what the tdap vaccine is, why it matters during pregnancy, when to get it, and how it helps protect your newborn during their most vulnerable weeks of life. The information below is based on guidance from well-established medical organizations and decades of vaccine safety data.
The tdap vaccine protects against three serious bacterial infections:
For pregnant people, the main focus of the tdap vaccine is pertussis, also known as whooping cough.
Whooping cough is not just a bad cough. In young babies, it can be life-threatening.
Newborns are at the highest risk because:
In infants, pertussis can cause:
Most babies who get whooping cough catch it from a parent, sibling, or caregiver who may not even realize they are infected.
The recommended time to get the tdap vaccine is between 27 and 36 weeks of pregnancy, ideally during the earlier part of this window.
Getting the tdap vaccine during this specific time allows your body to:
This process gives your newborn temporary immunity during their first few months of life, before they can receive their own vaccines.
Antibody levels decrease over time, so each pregnancy needs fresh protection.
When you receive the tdap vaccine during pregnancy:
This protection helps bridge the gap until your baby can start their own DTaP vaccine series at around 2 months of age.
Studies consistently show that maternal tdap vaccination:
Yes. The tdap vaccine has been studied extensively and is considered safe for both the pregnant person and the baby.
Large studies involving hundreds of thousands of pregnant individuals have found:
The vaccine does not contain live bacteria, so it cannot cause infection.
Most side effects are mild and temporary, such as:
Serious reactions are very rare. If you have a history of severe allergic reactions to vaccines, talk with your doctor before receiving the tdap vaccine.
If you miss the tdap vaccine during pregnancy, it is still recommended to get it as soon as possible after delivery.
However, it’s important to understand:
That’s why vaccination during pregnancy is the best option whenever possible.
Yes. This strategy is called “cocooning.”
Anyone who will be in close contact with your newborn should be up to date on their tdap vaccine, including:
This reduces the chance that someone will unknowingly pass whooping cough to your baby.
The tdap vaccine is safe while breastfeeding.
While breastfeeding does pass some antibodies to your baby, it does not replace getting the tdap vaccine during pregnancy. Both are helpful, but pregnancy vaccination provides stronger early protection.
It’s natural to feel concerned when reading about illnesses that affect newborns. The goal is not to cause fear, but to support informed, calm decision-making.
The key facts to remember:
Taking preventive steps is one of the most practical ways to protect your newborn’s health.
Pregnancy is also a good time to think about your own long-term health. If you have ongoing symptoms or concerns unrelated to pregnancy, you might consider doing a free, online symptom check for Cervical Cancer. Tools like this can help you decide whether it’s time to speak with a doctor, especially if something doesn’t feel right.
You should always speak to a doctor, midwife, or qualified healthcare provider if you:
Medical professionals can help you weigh benefits and risks based on your personal health history.
Making informed healthcare decisions during pregnancy is an act of care—for yourself and for your baby. The tdap vaccine is one of the simplest, most effective steps you can take to give your newborn a safer start.
(References)
* Maertens K, et al. Maternal Tdap vaccination and prevention of pertussis in infants: a systematic review and meta-analysis. Lancet Infect Dis. 2019 Mar;19(3):303-314. doi: 10.1016/S1473-3099(18)30722-1. Epub 2019 Jan 16. PMID: 30678950.
* Ding P, et al. Effectiveness of Prenatal Tdap Vaccination in Preventing Infant Pertussis in the United States: A Systematic Review and Meta-Analysis. J Pediatr. 2021 Sep;236:102-108.e6. doi: 10.1016/j.jpeds.2021.04.053. Epub 2021 May 3. PMID: 33947321; PMCID: PMC8492021.
* Meng Z, et al. Optimal timing of Tdap vaccination during pregnancy for passive immunity in newborns: a systematic review and meta-analysis. Hum Vaccin Immunother. 2022;18(1):1982633. doi: 10.1080/21645515.2021.1982633. Epub 2021 Jul 1. PMID: 34213031; PMCID: PMC8793077.
* Safi F, et al. Safety of Tdap vaccination during pregnancy: A systematic review and meta-analysis. Vaccine. 2017 Jan 5;35(2):203-214. doi: 10.1016/j.vaccine.2016.11.026. Epub 2016 Nov 28. PMID: 27914619.
* D'Andrea G, et al. Immunization of pregnant women with Tdap (tetanus, diphtheria, acellular pertussis) vaccine: a systematic review. Expert Rev Vaccines. 2016;15(7):903-12. doi: 10.1080/14760584.2016.1171811. Epub 2016 Apr 7. PMID: 27040439.
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