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Published on: 1/30/2026
The one timing mistake is getting the Tdap vaccine too early or waiting until after delivery, which protects the parent but not the baby in time; the optimal window is 27 to 36 weeks in every pregnancy so antibodies cross the placenta and shield newborns from pertussis during their highest risk period. There are several factors to consider; see below for what to do if you are past 36 weeks, why cocooning alone is not enough, safety evidence, and when to contact your clinician, since these details can shape your next steps.
When it comes to protecting newborns from serious illness, timing matters. One of the most common—and avoidable—mistakes parents and caregivers make involves the tdap vaccine. This single timing error can leave babies vulnerable during their most fragile months of life.
Below, we explain the mistake, why it matters, and how to make sure babies get the strongest protection possible—using clear language and guidance based on trusted medical consensus from organizations like the CDC and leading obstetric and pediatric groups.
The tdap vaccine protects against three serious diseases:
While all three diseases are dangerous, pertussis is the biggest concern for newborns. Babies are too young to start their own vaccine series until about 2 months of age, leaving a gap where they rely on protection from others.
The most critical mistake is getting the tdap vaccine too early—or waiting until after the baby is born.
The best time for a pregnant person to receive the tdap vaccine is:
Between 27 and 36 weeks of pregnancy—during every pregnancy
This window is not random. It is carefully chosen because:
If the tdap vaccine is given before 27 weeks, antibody levels may drop before delivery. That means:
Getting the tdap vaccine postpartum can still protect the parent—but it does not protect the baby in time. Newborns are at the highest risk for severe pertussis in the first weeks of life, before anyone realizes there is a problem.
In short:
Whooping cough doesn’t always look serious at first. In young infants, it can be subtle—but severe.
Babies with pertussis may:
Many infants who get very sick caught pertussis from a close contact who felt only mildly ill.
Medical experts agree on the 27–36 week timing based on years of research showing:
Importantly, the tdap vaccine is recommended during every pregnancy, even if:
This is because antibody levels decline over time, and each baby needs their own protection.
Not during pregnancy. Each pregnancy requires a new dose to ensure the baby gets enough antibodies.
Postpartum vaccination helps protect you, but it does not protect your newborn when they need it most.
This approach, called “cocooning,” helps—but it is not enough on its own. The strongest protection comes from antibodies passed directly from parent to baby before birth.
In addition to the correctly timed tdap vaccine, experts recommend:
These steps work best together, not alone.
Large studies involving hundreds of thousands of pregnant individuals show that the tdap vaccine:
Like any vaccine, mild side effects can happen, such as:
Serious reactions are rare. If you have a history of vaccine reactions or specific medical conditions, that’s a reason to speak to a doctor, not to skip protection altogether.
Pregnancy and early parenthood are times when health decisions can feel overwhelming. It’s okay to ask questions and double-check timing.
While you’re thinking about prevention, you might also consider doing a free, online symptom check for Cervical Cancer. It’s a simple way to stay informed and proactive about your health between routine screenings.
Contact a healthcare professional if:
The tdap vaccine is not just another checkbox—it’s a time-sensitive tool that protects babies when they are most vulnerable. Getting the timing right can make a real, measurable difference in a child’s first weeks of life. If there’s any uncertainty, the safest next step is simple: speak to a doctor and make a plan based on your individual health needs.
(References)
* Amirthalingam G, Campbell H, Ribeiro S, et al. Effectiveness of maternal pertussis vaccination in preventing infant pertussis in the United Kingdom: a retrospective case-control study. BMJ. 2016 Jan 20;352:i411. doi: 10.1136/bmj.i411. PMID: 26792257; PMCID: PMC4720970.
* Maertens K, Cabral T, De Schutter S, et al. Timing of maternal Tdap vaccination and antibody transfer to the infant. Pediatrics. 2016 Oct;138(4):e20161571. doi: 10.1542/peds.2016-1571. Epub 2016 Oct 3. PMID: 27708092.
* Eberhardt CS, Blanchard-Rohner G, Lemaître B, et al. Optimal Timing for Maternal Tdap Immunization to Maximize Pertussis Antibodies in Neonates. J Infect Dis. 2017 Aug 1;216(3):288-296. doi: 10.1093/infdis/jix272. PMID: 28552697.
* Donahue JG, Kieke BA, Mootrey GT, et al. Maternal Tdap Vaccination and Risk of Pertussis in Their Infants. Pediatrics. 2016 Jun;137(6):e20153835. doi: 10.1542/peds.2015-3835. Epub 2016 May 19. PMID: 27271811; PMCID: PMC4957421.
* Abu Raya B, Bamberger E, Shmueli A, et al. Effect of gestational age at Tdap immunization on maternal and cord blood anti-pertussis toxin antibody levels. Vaccine. 2015 Dec 16;33(51):7329-32. doi: 10.1016/j.vaccine.2015.11.028. Epub 2015 Nov 17. PMID: 26620779.
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