What Are the Current Treatment Options for Premature Rupture of Membranes?

Reviewed by Suo Lee, MD

Internal Medicine

Treatment of premature rupture of membranes depends on the baby's age and the mother's health, often involving careful monitoring, antibiotic therapy, and other supportive treatments to help both mother and baby.

Explanation

When the membranes break early, doctors work hard to keep both you and your baby safe. If the baby is born too early, doctors use a conservative approach. They give antibiotics to help stop infections from developing, which is very important for both you and your baby. If you are still early in your pregnancy, doctors may also provide steroids. Steroids help the baby’s lungs grow so they can work better if the baby is born before time. Another medicine, magnesium sulfate, might be used to help protect the baby’s brain if there is a risk of early birth. When you are closer to your due date and the baby is more developed, your doctor might wait for labor to begin naturally or may plan a delivery if signs of infection or distress are seen. Throughout, close observation is key. Regular check-ups allow doctors to monitor for any signs of infection or other problems and to decide the best time and way to deliver the baby safely.

(References)

Yudin MH, van Schalkwyk J, Eyk NV; INFECTIOUS DISEASES COMMITTEE; MATERNAL FETAL MEDICINE COMMITTEE. Antibiotic therapy in preterm premature rupture of the membranes. J Obstet Gynaecol Can. 2009 Sep;31(9):863-867. English, French. doi: 10.1016/S1701-2163(16)34305-5. PMID: 19941711.
Garite TJ. Management of premature rupture of membranes. Clin Perinatol. 2001 Dec;28(4):837-47. doi: 10.1016/s0095-5108(03)00081-2. PMID: 11817193.
Ruggieri S, Guido M, Taccaliti C, Latorre G, Gallini F, Forziati V, Caringella D, Giocolano A, Fantasia I. Conservative management of preterm premature rupture of membranes < 30 weeks of gestational age: Effectiveness of clinical guidelines implementation strategies. Eur J Obstet Gynecol Reprod Biol X. 2023 Jun 16;19:100209. doi: 10.1016/j.eurox.2023.100209. PMID: 37426941; PMCID: PMC10329107.

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