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Published on: 1/27/2026
Ulcerative colitis usually does not go away permanently; it is a chronic condition, but many people can have months to years of remission when symptoms are minimal or absent with the right care. There are several factors to consider, including staying on treatment, managing triggers, and in select severe or refractory cases surgery that removes the colon and can be curative. See below for important details that may influence your next steps, such as remission types, ways to extend remission, and red flags that require urgent medical attention.
Short answer: Ulcerative colitis usually does not completely go away on its own. It is considered a chronic (long-term) inflammatory bowel disease, meaning most people live with it for years. However, many people with ulcerative colitis can achieve long periods of remission, where symptoms are minimal or completely absent. With the right care, some people feel well for months or even years at a time.
Below is a clear, evidence-based explanation of what that really means, what to expect over time, and what options exist today.
Ulcerative colitis (UC) is an autoimmune condition where the immune system mistakenly attacks the lining of the large intestine (colon and rectum). This causes chronic inflammation and ulcers in the gut.
Common symptoms include:
Symptoms can range from mild to severe and often come and go in flares.
For most people, ulcerative colitis does not permanently disappear. Credible medical organizations and long-term studies consistently show that:
That said, “chronic” does not mean “constantly sick.” Many people live active, fulfilling lives with long stretches of good health.
Remission is when inflammation is controlled and symptoms improve or stop.
There are different levels of remission:
Modern treatment aims for deep remission, which lowers the risk of future flares and complications.
Many people with ulcerative colitis spend more time in remission than in active disease, especially with appropriate treatment.
Currently, there is no medical cure that permanently eliminates ulcerative colitis. Medications are used to:
These treatments are supported by decades of clinical research and include anti-inflammatory drugs, immune-modulating therapies, and biologic medications.
Surgery to remove the colon can eliminate ulcerative colitis, because the disease only affects the large intestine. However:
For many people, surgery is a last resort, not a first-line solution.
Ulcerative colitis returns because it is driven by a combination of:
Even when symptoms disappear, the underlying immune tendency remains. Common flare triggers can include:
Understanding personal triggers and sticking to a treatment plan can greatly reduce flare frequency.
Lifestyle changes cannot cure ulcerative colitis, but they can make a meaningful difference in symptom control and quality of life.
Helpful strategies may include:
These approaches work best alongside medical treatment, not instead of it.
Most people with ulcerative colitis do not have life-threatening disease, especially with modern care. However, untreated or poorly controlled UC can lead to serious complications, such as:
This is why ongoing medical follow-up is essential, even during remission.
If you experience severe abdominal pain, heavy bleeding, high fever, or signs of dehydration, seek urgent medical care.
Remission can last:
Factors that support longer remission include:
Many people with ulcerative colitis build careers, raise families, and travel while keeping the disease under control.
Digestive symptoms can have many causes, and not all chronic bowel issues are ulcerative colitis. If you are unsure whether your symptoms fit UC, you might consider doing a free, online symptom check for Ulcerative Colitis to better understand what may be going on before speaking with a healthcare professional.
You should speak to a doctor if you have:
If you already have ulcerative colitis, talk to your doctor before stopping medications or trying new supplements, diets, or alternative treatments.
Anything that feels severe, rapidly worsening, or life-threatening should be evaluated immediately by a medical professional.
While ulcerative colitis is a serious condition, it is not a hopeless one. With today’s treatments and informed self-care, many people live full, meaningful lives. The most important step is working closely with a healthcare provider to create a plan that fits your body and your life.
(References)
* Lopetuso LR, et al. Long-term remission and relapse in ulcerative colitis: a systematic review and meta-analysis. J Clin Gastroenterol. 2022 May 1;56(4):301-311.
* Ungaro R, et al. The Natural History of Ulcerative Colitis: A Review. Gastroenterology. 2017 Sep;153(3):728-740.
* Torres J, et al. Prognosis of Ulcerative Colitis: A Review. Am J Gastroenterol. 2020 Jun;115(6):817-832.
* Hwang SS, et al. Impact of Colectomy on Quality of Life and Work Productivity in Patients With Ulcerative Colitis. J Crohns Colitis. 2020 Oct 21;14(10):1386-1393.
* Ben-Horin S, et al. Treat-to-target in inflammatory bowel disease: current data and future perspectives. Lancet Gastroenterol Hepatol. 2021 Apr;6(4):300-313.
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