Our Services
Medical Information
Helpful Resources
Published on: 1/27/2026
Ulcerative colitis symptoms commonly include diarrhea that may contain blood or mucus, rectal bleeding, abdominal cramping with urgency or tenesmus, profound fatigue, and sometimes weight loss; some people also have joint pain, skin problems, eye inflammation, or mouth sores. Symptoms vary by how much of the colon is involved and whether you are in a flare or remission. There are several factors to consider, and some signs need urgent care, including heavy bleeding, severe abdominal pain or swelling, high fever, dehydration symptoms, a rapid heart rate, or black stools; see below for key details on what to watch for and how doctors confirm the diagnosis.
Ulcerative colitis is a long-term inflammatory bowel disease (IBD) that affects the lining of the large intestine (colon) and rectum. It causes inflammation and small ulcers that can lead to uncomfortable and sometimes serious symptoms. Understanding ulcerative colitis symptoms can help you recognize what’s going on in your body, seek care sooner, and manage the condition more effectively.
This guide explains the most common symptoms, how they may change over time, and when it’s important to speak to a doctor. The information is based on well-established medical understanding used by gastroenterology specialists and major health organizations.
Ulcerative colitis is considered an autoimmune-related condition. That means the immune system mistakenly attacks healthy tissue in the colon, leading to ongoing inflammation. Symptoms often come and go, with periods of flare-ups (active disease) and remission (few or no symptoms).
The symptoms can vary depending on:
Diarrhea is one of the most common symptoms of ulcerative colitis. It may:
Blood in the stool happens because ulcers in the colon can bleed. While this can be alarming, it’s a hallmark symptom of active disease.
Some people notice blood on toilet paper or in the toilet bowl even without diarrhea. This is more common when the rectum is involved, a form called ulcerative proctitis.
Pain is usually felt in the lower abdomen, especially on the left side. It may:
The pain comes from inflammation and muscle spasms in the colon.
Many people with ulcerative colitis feel a strong, sudden urge to have a bowel movement, even if little stool comes out. This feeling, called tenesmus, can be frustrating and disruptive to daily life.
Ongoing inflammation, frequent bowel movements, and poor sleep can lead to deep, persistent tiredness. Fatigue may also be related to:
This kind of fatigue is not always relieved by rest.
Some people experience other gut-related symptoms, including:
These symptoms are more common during moderate to severe flare-ups and may improve during remission.
Ulcerative colitis doesn’t only affect the colon. In some people, inflammation can impact other parts of the body. These are called extraintestinal symptoms.
These symptoms may appear during flare-ups and improve when the gut inflammation is controlled.
The type and severity of ulcerative colitis symptoms often depend on which part of the colon is affected:
Ulcerative proctitis (rectum only):
Left-sided colitis:
Extensive or pancolitis (entire colon):
Ulcerative colitis is usually a lifelong condition, but symptoms are not constant.
Treatment aims to reduce flare-ups and keep the disease in remission for as long as possible.
While many symptoms are manageable, some can indicate complications and should not be ignored. Speak to a doctor right away if you experience:
These symptoms can be life threatening and require urgent medical attention.
If you’re unsure whether what you’re experiencing could be related to ulcerative colitis, you might consider doing a free, online symptom check for Ulcerative Colitis. Tools like this can help you organize your symptoms and decide whether it’s time to speak with a healthcare professional.
Symptoms alone are not enough to diagnose ulcerative colitis. A doctor may recommend:
Early diagnosis can make treatment more effective and reduce complications.
Many people with ulcerative colitis lead full, active lives. Management often includes:
Symptoms may change over time, so ongoing care is important.
Ulcerative colitis symptoms can range from mild to severe and may affect more than just your digestive system. Knowing what to look for helps you take symptoms seriously without unnecessary fear. If something feels off, trust your instincts and speak to a doctor, especially about symptoms that are persistent, worsening, or could be life threatening.
Getting informed, checking your symptoms, and working with a healthcare professional are key steps toward managing ulcerative colitis and protecting your long-term health.
(References)
* https://pubmed.ncbi.nlm.nih.gov/35086815/
* https://pubmed.ncbi.nlm.nih.gov/30006323/
* https://pubmed.ncbi.nlm.nih.gov/37920150/
* https://pubmed.ncbi.nlm.nih.gov/29033379/
* https://pubmed.ncbi.nlm.nih.gov/34183861/
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.