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Published on: 1/27/2026
Common ulcerative colitis symptoms include chronic diarrhea, blood or mucus in the stool, abdominal cramping with an urgent need to go, and fatigue; some people also have weight loss, low-grade fever during flares, and symptoms outside the gut such as joint pain, skin changes, or eye irritation. Severity and location in the colon affect symptoms, and warning signs like heavy bleeding, severe abdominal pain, dehydration, high fever, a rapid heart rate, or a sudden worsening mean you should seek urgent care. There are several factors to consider; see below for fuller details that can guide your next steps and when to contact a doctor.
Ulcerative colitis is a long-term inflammatory condition that affects the large intestine (colon) and rectum. It is a form of inflammatory bowel disease (IBD). Symptoms can vary widely from person to person and may change over time, ranging from mild and manageable to more serious. Understanding the symptoms can help you recognize when something isn’t right and take appropriate next steps.
This guide explains the common, less common, and serious symptoms of ulcerative colitis in clear, everyday language, based on widely accepted medical knowledge from gastroenterology research and clinical guidelines.
Ulcerative colitis causes ongoing inflammation and small ulcers in the lining of the colon. These ulcers can bleed and produce mucus. Because the colon plays a key role in absorbing water and forming stool, inflammation there often leads to bowel-related symptoms.
Symptoms usually develop gradually, not suddenly. Many people experience periods of flare-ups (when symptoms worsen) and remission (when symptoms improve or disappear for a time).
Persistent diarrhea is one of the hallmark symptoms of ulcerative colitis.
This happens because inflammation prevents the colon from absorbing water properly.
Blood in the stool is a key sign that distinguishes ulcerative colitis from many other digestive issues.
While seeing blood can be alarming, it is a common symptom of ulcerative colitis and should always be evaluated by a doctor.
The colon normally produces small amounts of mucus, but inflammation increases this production.
Pain is often linked to bowel movements.
Inflammation can cause a strong, sudden urge to use the bathroom.
Ulcerative colitis doesn’t only affect the gut. Ongoing inflammation can impact the entire body.
Chronic inflammation, frequent bathroom trips, and poor sleep can lead to ongoing tiredness.
Weight loss may occur due to:
Abdominal discomfort and nausea can reduce the desire to eat, especially during flare-ups.
Low-grade fevers can occur when inflammation is active.
Some people with ulcerative colitis experience symptoms beyond the colon. These are known as extraintestinal manifestations.
Certain inflammatory skin conditions can occur, including:
Inflammation can affect the eyes, leading to:
Eye symptoms should always be checked by a healthcare professional promptly.
While many symptoms can be managed with medical care, some signs may indicate complications.
Seek urgent medical help if you experience:
These may signal serious conditions such as severe inflammation, infection, or toxic megacolon, which require immediate medical care.
Ulcerative colitis always starts in the rectum, but it can spread.
Some symptoms of ulcerative colitis overlap with conditions like irritable bowel syndrome (IBS), infections, or hemorrhoids. However, ulcerative colitis involves ongoing inflammation, which requires medical diagnosis and monitoring.
If you are unsure whether your symptoms fit ulcerative colitis, you might consider doing a free, online symptom check for Ulcerative Colitis to better understand what may be going on before speaking with a healthcare professional.
Identifying ulcerative colitis symptoms early can help:
Ulcerative colitis is a chronic condition, but many people live full, active lives with proper care and monitoring.
If you are experiencing ongoing diarrhea, blood in your stool, abdominal pain, or unexplained fatigue, it is important to speak to a doctor. A healthcare professional can evaluate your symptoms, run appropriate tests, and discuss treatment options if needed.
Do not delay medical care if symptoms feel severe, worsen quickly, or could be life-threatening. Early medical attention can make a meaningful difference in outcomes.
Ulcerative colitis symptoms often involve chronic diarrhea, blood or mucus in the stool, abdominal pain, urgency, and fatigue. Symptoms can range from mild to serious and may affect more than just the digestive system. Paying attention to changes in your body and seeking medical guidance is the best way to protect your health and well-being.
(References)
* Park SH, Kim YS, Kim YH, et al. Ulcerative Colitis: Clinical Presentation, Diagnosis, and Treatment. Korean J Gastroenterol. 2017 Aug;70(2):107-117. doi: 10.4166/kjg.2017.70.2.107. PMID: 28838274. https://pubmed.ncbi.nlm.nih.gov/28838274/
* Ungaro R, Mehandru S, Allen PB, Colombel JF. Ulcerative Colitis: Pathophysiology and Clinical Manifestations. Gastroenterol Clin North Am. 2018 Jun;47(2):291-306. doi: 10.1016/j.gtc.2018.01.002. PMID: 29747714. https://pubmed.ncbi.nlm.nih.gov/29747714/
* Kaplan GG, Kaplan LJ, Kaplan GD, Drossman DA. A contemporary view of ulcerative colitis diagnosis and management. World J Gastroenterol. 2017 Oct 7;23(37):6785-6799. doi: 10.3748/wjg.v23.i37.6785. PMID: 29090074. https://pubmed.ncbi.nlm.nih.gov/29090074/
* Roda G, Sartini A, Capannolo A, et al. Ulcerative Colitis: Clinical Presentation, Diagnosis, and Management. Discov Med. 2020 Jan-Feb;29(156):25-34. PMID: 32247155. https://pubmed.ncbi.nlm.nih.gov/32247155/
* Katz S, Pardi DS, Tremaine WJ. Ulcerative colitis: Clinical manifestations, diagnosis, and prognosis. Med Clin North Am. 2011 May;95(3):611-26. doi: 10.1016/j.mcna.2011.02.001. PMID: 21474013. https://pubmed.ncbi.nlm.nih.gov/21474013/
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