Doctors Note Logo

Published on: 2/10/2026

Ulcerative Colitis in Women 65+: Symptoms You Shouldn’t Ignore

In women 65 and older, ulcerative colitis can be subtle and should be suspected with persistent diarrhea, blood or mucus in the stool, lower abdominal cramping, unrelenting fatigue, unintended weight loss, or new bowel habit changes, sometimes with joint, skin, or eye issues. Seek prompt medical care for ongoing rectal bleeding, severe or worsening abdominal pain, fever with bowel symptoms, signs of dehydration, or extreme fatigue or shortness of breath; there are several factors to consider, and key details on look-alike conditions, testing, and treatment options are outlined below.

answer background

Explanation

Ulcerative Colitis in Women 65+: Symptoms You Shouldn't Ignore

Ulcerative Colitis is a long-term inflammatory bowel disease (IBD) that affects the lining of the large intestine (colon) and rectum. While it is often diagnosed in younger adults, a significant number of women are diagnosed after age 65—either for the first time or as a recurrence after years of remission. Because symptoms in older women can look different and may overlap with other common age-related conditions, it's important to recognize warning signs early and know when to speak to a doctor.

This guide explains what Ulcerative Colitis can look like in women 65 and older, which symptoms should not be ignored, and why timely care matters—without unnecessary alarm.


Why Ulcerative Colitis Can Be Different After 65

As we age, the immune system changes, the gut becomes more sensitive, and other health conditions or medications may complicate symptoms. In women over 65, Ulcerative Colitis may:

  • Begin more subtly than in younger people
  • Be mistaken for infections, hemorrhoids, or medication side effects
  • Carry higher risks if inflammation goes untreated

Older women are also more likely to be managing other conditions such as heart disease, osteoporosis, or diabetes, which can affect how Ulcerative Colitis presents and how it's treated.


Common Symptoms of Ulcerative Colitis in Women 65+

Some symptoms are classic, while others are more easily overlooked. If you notice a pattern or combination of the following, it's worth paying attention.

1. Ongoing Diarrhea

Diarrhea is the most common symptom of Ulcerative Colitis. In older women, it may be:

  • Frequent loose or watery stools
  • More urgent, with little warning
  • Worse at night or early morning

Occasional diarrhea happens to everyone, but persistent diarrhea lasting more than a few weeks is not normal and should be discussed with a healthcare provider.


2. Blood or Mucus in the Stool

Seeing blood in the stool can be alarming, but it's also one of the clearest signs of Ulcerative Colitis. Blood may appear:

  • Bright red on the toilet paper
  • Mixed with stool
  • Along with mucus

While hemorrhoids are common, especially with age, blood that continues or worsens should never be ignored. A doctor can help determine the cause.


3. Abdominal Pain or Cramping

Women over 65 with Ulcerative Colitis may experience:

  • Cramping or aching in the lower abdomen
  • Pain that improves after a bowel movement
  • Ongoing discomfort rather than sharp pain

This pain is caused by inflammation in the colon. While it may be mild at first, ongoing pain deserves medical attention.


4. Fatigue That Doesn't Improve With Rest

Chronic inflammation takes a toll on the body. Many women with Ulcerative Colitis report:

  • Feeling unusually tired
  • Low energy even after sleep
  • Difficulty keeping up with daily activities

Fatigue may also be related to anemia (low red blood cells), which can happen due to intestinal bleeding. This is a common but often missed complication in older adults.


5. Unintended Weight Loss or Loss of Appetite

Weight loss is not a normal part of aging. In Ulcerative Colitis, it can happen because:

  • Eating causes discomfort
  • The body isn't absorbing nutrients well
  • Inflammation suppresses appetite

Even modest, unexplained weight loss should be discussed with a doctor, especially if combined with bowel changes.


6. Changes in Bowel Habits

Ulcerative Colitis doesn't always cause constant diarrhea. Some women notice:

  • Alternating diarrhea and constipation
  • Narrow or smaller stools
  • A constant feeling of needing to use the bathroom, even when the bowel is empty

These changes may come on gradually and can be mistaken for "normal aging," but they are not something to dismiss.


7. Symptoms Outside the Gut

Ulcerative Colitis is a whole-body inflammatory condition. In women over 65, it may also cause:

  • Joint pain or stiffness
  • Skin rashes or sores
  • Eye redness or irritation

These symptoms may seem unrelated to digestion but can be important clues.


Symptoms That Need Prompt Medical Attention

Without being alarmist, some symptoms should be addressed quickly, especially in older adults:

  • Persistent rectal bleeding
  • Severe or worsening abdominal pain
  • Fever along with bowel symptoms
  • Signs of dehydration (dry mouth, dizziness, dark urine)
  • Extreme fatigue or shortness of breath

If any of these occur, speak to a doctor as soon as possible, as they may signal complications that need timely treatment.


Why Early Recognition Matters

When Ulcerative Colitis is diagnosed and managed early, many women live full, active lives. Treatment can:

  • Reduce inflammation
  • Control symptoms
  • Lower the risk of complications such as anemia, hospitalization, or colon damage

In women over 65, early care is especially important because recovery can take longer, and complications may be more serious if inflammation goes untreated.


How Ulcerative Colitis Is Diagnosed

A doctor may use a combination of:

  • Medical history and symptom review
  • Blood tests to check for inflammation or anemia
  • Stool tests to rule out infection
  • Imaging or colonoscopy to look at the colon lining

These tests help confirm Ulcerative Colitis and rule out other causes of symptoms that are more common with age.


A Helpful First Step: Checking Your Symptoms

If you're noticing persistent digestive symptoms and want to better understand what might be happening, using a free Ulcerative Colitis symptom checker can help you identify patterns in your symptoms and prepare meaningful questions before your doctor's appointment. While it's not a substitute for professional medical advice, it can be a valuable tool to help you communicate your concerns more clearly and ensure nothing important gets overlooked.


Living Well With Ulcerative Colitis After 65

Many women worry that a diagnosis will drastically change their lives. While Ulcerative Colitis is a serious condition, it is also manageable. Treatment plans are individualized and may include:

  • Anti-inflammatory medications
  • Immune-modulating therapies
  • Dietary adjustments
  • Monitoring for complications

Doctors take age, overall health, and other medications into account when recommending treatment, aiming to balance effectiveness with safety.


When to Speak to a Doctor

If you are a woman over 65 and notice ongoing digestive changes, blood in your stool, unexplained fatigue, or weight loss, it's important to speak to a doctor. Any symptom that could be life-threatening or serious—such as heavy bleeding, severe pain, or signs of dehydration—should be addressed promptly.

Listening to your body and seeking care early is not overreacting; it's a practical step toward protecting your health.


Final Thoughts

Ulcerative Colitis in women 65+ can be easy to overlook, but recognizing the symptoms you shouldn't ignore can make a real difference. With accurate diagnosis, appropriate treatment, and regular medical care, many women continue to enjoy a good quality of life. If something feels off or persistent, trust your instincts—and talk with a healthcare professional who can guide you forward.

(References)

  • * Agah, S., et al. "Inflammatory bowel disease in the elderly: a review." *World J Gastroenterol*, 2011 May 14;17(18):2279-90. PMID: 21606927.

  • * Ananthakrishnan, A. N., et al. "Inflammatory Bowel Disease in the Elderly: A Unique Clinical Challenge." *Dig Dis Sci*, 2017 Jul;62(7):1694-1702. PMID: 28516314.

  • * Hou, J. K., et al. "Diagnosis and Management of Inflammatory Bowel Disease in the Elderly." *Gastroenterology*, 2019 Jun;156(8):2149-2162.e1. PMID: 30910406.

  • * Ben-Horin, S., et al. "Clinical features and outcome of inflammatory bowel disease in elderly patients." *J Crohns Colitis*, 2011 Apr;5(2):112-8. PMID: 21453880.

  • * Ma, C., et al. "Late-onset inflammatory bowel disease: a systematic review." *World J Gastroenterol*, 2018 Jan 14;24(2):167-176. PMID: 29386762.

Thinking about asking ChatGPT?Ask me instead

Tell your friends about us.

We would love to help them too.

smily Shiba-inu looking

For First Time Users

What is Ubie’s Doctor’s Note?

We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.

Learn more about diseases

Ulcerative Colitis

Was this page helpful?

Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.