Our Services
Medical Information
Helpful Resources
Published on: 1/14/2026
There are several factors to consider. Unrefreshing sleep often means your brain is not completing deep and REM sleep tasks like waste clearance, repair, and memory consolidation, which can be disrupted by fragmented sleep, circadian misalignment, stress, certain medications or substances, sleep apnea or restless legs, and medical issues including liver disease with encephalopathy, ascites, hyponatremia, thyroid problems, chronic pain, and some neurological conditions. Key warning signs and step by step fixes are outlined below and can shape your next steps, from sleep hygiene changes and a sleep study to urgent medical evaluation if there is severe daytime sleepiness, confusion, loud snoring with gasping, chest pain, or swelling.
Waking up still tired—despite spending enough hours in bed—is frustrating. If your sleep feels unrefreshing, it could mean your brain isn’t completing its vital nighttime tasks. During healthy sleep, your brain clears out toxins, balances chemicals, stores memories and resets for the day ahead. When this “finish line” isn’t reached, you feel foggy, irritable and drained.
Below, we explain what “unrefreshing sleep” really means, common causes, when to seek help and simple steps you can take tonight to help your brain do its job.
Refreshing sleep isn’t just about clocking 8 hours. It’s about moving through sleep stages in the right pattern:
When these stages are disrupted or shortened, your brain can’t finish detoxifying, rebuilding and organizing memories. The result? You wake up feeling as if you never slept at all.
Poor Sleep Quality
Sleep Disorders
Circadian Misalignment
Stress and Mental Health
Medications and Substances
Sometimes, unrefreshing sleep signals an underlying health problem that directly affects brain chemistry or fluid balance.
Chronic liver disease (such as cirrhosis) reduces the liver’s ability to filter toxins. These build up in the blood and reach your brain, causing confusion, sleep–wake reversal and nonrestorative sleep.
(Reference: Butterworth RF. Hepatic encephalopathy: a guide for the clinician… Nat Clin Pract Gastroenterol Hepatol, 2007.)
Fluid accumulation in the abdomen can change electrolyte levels and pressure in your body. This can worsen brain fog and daytime sleepiness. (Reference: Runyon BA. Management of adult patients with ascites due to cirrhosis… Hepatology, 2009.)
Low sodium levels cause swelling of brain cells, leading to headache, nausea, confusion and poor sleep quality. This condition has been linked with higher mortality in liver-disease patients. (Reference: Kim WR & Biggins SW. Hyponatremia and mortality among patients on the liver-transplant… N Engl J Med, 2008.)
Other medical causes include:
Not every rough night requires a doctor’s visit. But consider prompt evaluation if you have:
If you’re unsure what’s happening, you might consider doing a free, online symptom check for to help identify possible causes.
Establish a Consistent Routine
Optimize Your Sleep Environment
Mind Your Diet and Drinks
Wind Down with Relaxation
Exercise Regularly
Address Underlying Health Issues
If unrefreshing sleep persists despite lifestyle changes, it’s time to involve a professional. You should speak to a doctor if you notice:
Sleep is essential for both your body and brain. When you don’t feel rested, you’re missing critical maintenance and repairs. Taking steps to improve sleep hygiene, address medical concerns and stick to a schedule will help your brain cross the finish line every night.
Remember: lasting relief often comes from both lifestyle tweaks and medical evaluation. If you have any life-threatening or serious symptoms, please seek immediate medical attention or call emergency services.
(References)
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.