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Published on: 1/14/2026
Persistent urgent diarrhea, especially at night, with blood or mucus, abdominal cramping, tenesmus, unexplained weight loss, and fatigue suggests inflammatory bowel disease rather than IBS; extra clues outside the gut include joint pain or swelling, skin rashes, and eye inflammation. There are several factors to consider; see below for the key differences from IBS and the specific tests and red flags that guide next steps, including fecal calprotectin, blood work for inflammation and anemia, colonoscopy with biopsy, and imaging.
Feeling an urgent, uncontrollable need to poop can be alarming. While occasional urgency often stems from diet, infection, or stress, persistent or severe urgency may signal inflammatory bowel disease (IBD)—including Crohn’s disease and ulcerative colitis. Recognizing key symptoms early can help you get the right diagnosis and treatment.
Not every bout of urgency means IBD. Watch for these persistent or severe signs:
IBD can affect more than your bowels. Noticeable signs elsewhere include:
According to the 2019 ECCO-ESGAR guidelines¹, diagnosing IBD involves a combination of clinical, lab, endoscopic, and imaging tests:
Irritable bowel syndrome (IBS) can also cause urgency, diarrhea, and cramping. A 2012 study³ showed that up to 30% of IBD patients in remission still report IBS-type symptoms. Key differences:
Other causes of urgency include infections (e.g., C. difficile), medication side effects, and ischemic colitis, so professional evaluation is important.
Consider prompt medical evaluation if you experience:
Early diagnosis can prevent complications such as strictures, fistulas, malnutrition, and increased risk of colorectal cancer.
Only a healthcare professional can diagnose IBD. If any of the above symptoms are new, worsening, or cause you concern—especially if life-threatening signs (high fever, severe pain, dehydration) appear—speak to a doctor right away. Early intervention leads to better long-term outcomes and quality of life.
¹ Maaser C, Sturm A, Vavricka SR, et al. ECCO-ESGAR Guideline for Diagnostic Assessment in IBD. J Crohns Colitis. 2019;
² Merli M, Giannelli V, De Santis A, et al. Thrombocytopenia is associated with increased mortality in… Clin Gastroenterol Hepatol. 2011;
³ Halpin SJ, Ford AC. Prevalence of IBS-type symptoms in IBD. Am J Gastroenterol. 2012.
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