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Published on: 1/29/2026

What does it mean when stomach pain doesn’t go away for weeks?

Persistent stomach pain for more than 2 to 3 weeks usually means your body needs a closer look, with common causes ranging from gastritis, ulcers, reflux, IBS and constipation to food intolerances, lingering infections like H. pylori, inflammatory conditions such as IBD, gallbladder or pancreas problems, and the effects of stress. There are several factors to consider and some red flags that need urgent care, like weight loss, persistent vomiting, blood in or black stools, severe night pain, fever, trouble swallowing, or yellowing skin or eyes; see the complete guidance on what to do next, what to track, and which tests doctors use below.

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Explanation

Stomach pain that lasts for weeks can be confusing and frustrating. While many people experience short-lived stomach discomfort from things like stress or a mild stomach bug, pain that doesn't go away deserves closer attention. Persistent stomach pain doesn't always mean something serious, but it does mean your body is asking for a deeper look.

Below is a clear, medically grounded explanation of what long-lasting stomach pain may mean, what common causes are, when to be concerned, and what steps you can take next—written in plain language and based on widely accepted medical knowledge.


What Counts as Long-Lasting Stomach Pain?

Doctors generally consider stomach pain that lasts longer than 2–3 weeks to be persistent or chronic, especially if it:

  • Happens most days
  • Keeps coming back
  • Interferes with daily activities, sleep, or eating

This type of stomach pain is different from sudden pain that resolves within a few hours or days.


Common Reasons Stomach Pain Doesn't Go Away

Persistent stomach pain can come from many causes, ranging from functional (how the body works) to structural (changes in organs or tissues). Below are some of the most common explanations.

1. Digestive System Conditions

Many ongoing stomach pain issues come from the digestive tract.

Common possibilities include:

  • Gastritis – inflammation of the stomach lining, often linked to medications, alcohol, or infection
  • Peptic ulcers – sores in the stomach or upper intestine that can cause burning or gnawing pain
  • Acid reflux (GERD) – stomach acid irritating the esophagus, sometimes felt as upper stomach pain
  • Irritable Bowel Syndrome (IBS) – a functional gut disorder that causes recurring stomach pain, bloating, diarrhea, or constipation
  • Chronic constipation – can cause pressure, cramping, and discomfort that lingers

These conditions are common and treatable, but they usually require proper diagnosis.


2. Food-Related Causes

Some people experience ongoing stomach pain due to how their body reacts to certain foods.

This may involve:

  • Food intolerances, such as lactose or fructose intolerance
  • Sensitivity to fatty, spicy, or acidic foods
  • Celiac disease, an immune reaction to gluten that damages the small intestine

Food-related stomach pain often improves when the trigger food is removed—but not always without guidance.


3. Infections That Don't Fully Resolve

Certain infections can lead to stomach pain that lasts weeks.

Examples include:

  • Helicobacter pylori (H. pylori) infection, which can inflame the stomach lining and cause ulcers
  • Post-infectious gut changes, where pain continues even after a stomach bug is gone

These infections usually require medical testing and prescription treatment.


4. Inflammation in the Abdomen

Inflammation can cause persistent stomach pain and may affect different organs.

Possible causes include:

  • Inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis
  • Chronic pancreatitis
  • Gallbladder disease, including gallstones

Inflammatory conditions often come with additional symptoms, such as fatigue, appetite changes, or bowel habit changes.


5. Stress, Anxiety, and the Gut-Brain Connection

The digestive system is closely connected to the brain. Long-term stress or anxiety can cause real, physical stomach pain.

This may show up as:

  • Cramping or aching stomach pain
  • Bloating or nausea
  • Pain that worsens during stressful periods

Even when stress plays a role, the pain is still real and deserves proper care.


When Stomach Pain May Be More Serious

Most causes of long-lasting stomach pain are manageable, but some situations require prompt medical attention.

Speak to a doctor right away or seek urgent care if stomach pain is accompanied by:

  • Unintentional weight loss
  • Persistent vomiting
  • Blood in stool or black, tar-like stools
  • Severe pain that wakes you from sleep
  • Fever or chills
  • Difficulty swallowing
  • Yellowing of the skin or eyes

These signs can point to potentially serious or life-threatening conditions and should never be ignored.


Why You Shouldn't Ignore Weeks of Stomach Pain

Ignoring ongoing stomach pain can lead to:

  • Delayed diagnosis of treatable conditions
  • Worsening inflammation or complications
  • Reduced quality of life due to ongoing discomfort

Even when the cause turns out to be mild, knowing what's happening can provide relief and peace of mind.


How Doctors Evaluate Persistent Stomach Pain

When you speak to a doctor, they may ask about:

  • Location and type of stomach pain
  • Foods that make it better or worse
  • Bowel habits
  • Medications and supplements
  • Stress levels and lifestyle

Depending on your symptoms, they may recommend:

  • Blood tests
  • Stool tests
  • Breath tests
  • Imaging (such as ultrasound or CT scan)
  • Endoscopy or colonoscopy

Not everyone needs extensive testing, but evaluation is important when pain persists.


Steps You Can Take Right Now

If you've had stomach pain for weeks, consider these practical steps:

  • Track your symptoms (when they occur, what you eat, and how severe they are)
  • Avoid excessive use of pain relievers, especially NSAIDs, unless advised by a doctor
  • Eat regular, balanced meals and avoid known trigger foods
  • Manage stress, sleep, and hydration

If you're unsure what might be causing your discomfort, using a free abdominal pain symptom checker can help you better understand your symptoms and prepare informed questions for your doctor.


The Bottom Line

Stomach pain that doesn't go away for weeks is a signal that something needs attention. While many causes are common and treatable, persistent pain should not be brushed off. The key is balanced action—staying calm, informed, and proactive.

If your stomach pain is ongoing, worsening, or paired with concerning symptoms, speak to a doctor as soon as possible. This is especially important if there is any chance the cause could be serious or life threatening.

Listening to your body and seeking proper medical guidance is the best way to protect your health and get lasting relief.

(References)

  • * Kappus MR, Chey WD. Chronic Abdominal Pain: A Clinical Review. Gastroenterology. 2019 Apr;156(5):1323-1339. doi: 10.1053/j.gastro.2019.01.054. Epub 2019 Feb 1. PMID: 30716279.

  • * Black CJ, Storr M, Coffin B. Irritable Bowel Syndrome: A Comprehensive Review. Gastroenterol Clin North Am. 2020 Jun;49(2):227-243. doi: 10.1016/j.gtc.2020.01.001. PMID: 32389146.

  • * Ghosal L, Stobaugh D, Kussman J, Amato J, Dube A, Runkel D, Miskulin J, Bynum L, Vairamuthu S. Abdominal Pain of Unknown Origin in Adults: Evaluation. Am Fam Physician. 2019 Sep 15;100(6):357-366. PMID: 31524317.

  • * Sperber AD, Drossman DA. Functional Abdominal Pain Syndromes in Adults: Current Understanding and Treatment. Am J Gastroenterol. 2017 May;112(5):713-723. doi: 10.1038/ajg.2017.92. PMID: 28397750.

  • * Strate LL, Lopez-Millan R. Chronic Abdominal Pain. Surg Clin North Am. 2017 Aug;97(4):781-797. doi: 10.1016/j.suc.2017.03.003. PMID: 28734509.

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