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Published on: 4/7/2025

How Can an Yeast Fungal Infection Affect My Toenail, and What Are the Treatment Options?

An yeast fungal infection in your toenail can make it thick, discolored, and brittle, and treatment options include topical antifungal creams or nail lacquers and, in more serious cases, oral medications.

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Explanation

When a yeast fungus, often from Candida species, affects your toenail, it can change the nail’s look and feel. The infected toenail might become thick, feel crumbly, or display unusual colors such as yellow or white. It might even start to lift away from the nail bed, which can sometimes cause discomfort when you walk or wear shoes. To treat this type of infection, doctors usually start with topical antifungal treatments. These come as creams, solutions, or nail lacquers that you apply directly to the toe, aiming to reduce the fungus on the nail surface. For more stubborn or deeper infections, your doctor might suggest taking an oral antifungal medication that works from inside your body. Although these pills, such as terbinafine or itraconazole, are often very effective, they might have side effects and will be prescribed carefully based on your overall health. Keeping your feet clean and dry also helps because fungi thrive in moist environments. Always talk with a healthcare provider to decide on the treatment that works best for you and to monitor the infection over time.

(References)

  • Updated 2022 Dec 2]. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK279547/
  • Kreijkamp-Kaspers S, Hawke K, Guo L, Kerin G, Bell-Syer SE, Magin P, Bell-Syer SV, van Driel ML. Oral antifungal medication for toenail onychomycosis. Cochrane Database Syst Rev. 2017 Jul 14;7(7):CD010031. doi: 10.1002/14651858.CD010031.pub2. PMID: 28707751; PMCID: PMC6483327.

  • Yousefian F, Smythe C, Han H, Elewski BE, Nestor M. Treatment Options for Onychomycosis: Efficacy, Side Effects, Adherence, Financial Considerations, and Ethics. J Clin Aesthet Dermatol. 2024 Mar;17(3):24-33. PMID: 38495549; PMCID: PMC10941855.

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