Calcifilaxis Quiz

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Caroline M. Doan

Caroline M. Doan, DO

Internal medicine

Yukiko Ueda

Yukiko Ueda, MD

Dermatology

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Learn more about Calcifilaxis

Content updated on Sep 20, 2022

What is calcifilaxis?

Calciphylaxis is a rare disorder, most commonly seen in people with chronic end-stage kidney disease, in which calcium deposits abnormally accumulate in the blood vessels. This causes blood clots, and the decreased blood flow can lead to painful skin ulcers, which can be a potential source for serious infections that can lead to death.

Symptoms of calcifilaxis

  • Kidney failure on dialysis

  • Skin redness or red bumpy rashes

  • Affected area of skin has stinging or tingling

  • Black/blue/brown spots or moles, on the skin and lining of the mouth

Questions your doctor may ask to check for calcifilaxis

Your doctor may ask these questions to diagnose calcifilaxis

  • Are you currently on dialysis (hemodialysis, peritoneal dialysis, etc)?

  • Do you have red skin or red spots on the skin?

  • Do you have any pain or tingling in the affected areas of the skin?

  • Are there black, blue, or brown spots on the skin or elsewhere? (Including moles)

Treatment for calcifilaxis

While there is no cure for calciphylaxis, symptoms can be managed with wound care and pain control, as well as medications like sodium thiosulfate and other treatments to decrease calcium buildup.

View the symptoms of Calcifilaxis

References

  • Raimondi N, Del Vecchio JJ, Ghioldi M, Uzair E. Calcifilaxis [Calciphylaxis]. Medicina (B Aires). 2017;77(4):331-333. Spanish. PMID: 28825580.

    http://www.medicinabuenosaires.com/PMID/28825580.pdf

Medically Reviewed By:

Caroline M. Doan

Caroline M. Doan, DO

Internal medicine

Yukiko Ueda

Yukiko Ueda, MD

Dermatology

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