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What is Chorioamnionitis?
Chorioamnionitis is a pregnancy condition where the tissues and fluid around the fetus (unborn baby) become infected. This typically occurs in labor after the water bag (amniotic sac) is broken, but can occur before this as well. This is a serious condition that requires delivery of the fetus to protect both the mother and the baby.
Typical Symptoms of Chorioamnionitis
- Increased vaginal discharge that is smelly
- Currently pregnant
- Feel my child is moving less. (Decreased fetal movements)
- Feel like water has broken/amniotic fluid is coming out
- Increase in vaginal discharge
- Abnormal color, amount or odor of vaginal discharge
- Fever
- Stomach or abdominal pain accompanied by a hard abdomen
Diagnostic Questions for Chorioamnionitis
Your doctor may ask these questions to check for this disease:
- Has the vaginal discharge odor worsened recently?
- Are you pregnant?
- Is your child moving less?
- Do you feel like your water has broken?
- Have you had more vaginal discharge lately?
Treatment of Chorioamnionitis
Treatment is with antibiotics and prompt delivery of the fetus. The newborn will need evaluation by pediatricians and likely further antibiotics.
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Smelly vaginal discharge
- Vaginal discharge odor
- My baby isn't moving as much
- There is a large amount of vaginal discharge with bad smell
- I think my water has broken
- Excessive amount of vaginal discharge
- Lots of vaginal discharge
- I feel like my baby has stopped moving
- Leaking fluid followed by contractions
- Increase in vaginal discharge
- Uncontrollable leaking from the vagina
- Increased vaginal discharge
- Rupture of membranes
- Excessive vaginal discharge
- Premature rupture of the membranes
See full list
Symptoms Related to Chorioamnionitis
Diseases Related to Chorioamnionitis
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol. 2015 Oct;213(4 Suppl):S29-52. doi: 10.1016/j.ajog.2015.08.040. PMID: 26428501; PMCID: PMC4774647.
https://www.ajog.org/article/S0002-9378(15)00910-2/fulltextTita AT, Andrews WW. Diagnosis and management of clinical chorioamnionitis. Clin Perinatol. 2010 Jun;37(2):339-54. doi: 10.1016/j.clp.2010.02.003. PMID: 20569811; PMCID: PMC3008318.
https://www.sciencedirect.com/science/article/abs/pii/S0095510810000217?via%3DihubPeng CC, Chang JH, Lin HY, Cheng PJ, Su BH. Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis. Pediatr Neonatol. 2018 Jun;59(3):231-237. doi: 10.1016/j.pedneo.2017.09.001. Epub 2017 Sep 19. PMID: 29066072.
https://www.pediatr-neonatol.com/article/S1875-9572(17)30027-X/fulltextJain VG, Willis KA, Jobe A, Ambalavanan N. Chorioamnionitis and neonatal outcomes. Pediatr Res. 2022 Jan;91(2):289-296. doi: 10.1038/s41390-021-01633-0. Epub 2021 Jul 1. PMID: 34211129; PMCID: PMC8720117.
https://www.nature.com/articles/s41390-021-01633-0Beck C, Gallagher K, Taylor LA, Goldstein JA, Mithal LB, Gernand AD. Chorioamnionitis and Risk for Maternal and Neonatal Sepsis: A Systematic Review and Meta-analysis. Obstet Gynecol. 2021 Jun 1;137(6):1007-1022. doi: 10.1097/AOG.0000000000004377. PMID: 33957655; PMCID: PMC8905581.
https://journals.lww.com/greenjournal/Abstract/2021/06000/Chorioamnionitis_and_Risk_for_Maternal_and.7.aspxACOG Committee Opinion
https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2017/08/intrapartum-management-of-intraamniotic-infection