Dermatofibrosarcoma Protuberans Quiz

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Learn more about Dermatofibrosarcoma protuberans

Content updated on Nov 2, 2022

What is dermatofibrosarcoma protuberans?

This is a very rare skin cancer. It is slow growing and rarely spreads beyond the skin, but may recur even after it is removed. It develops from the connective tissue of the middle layer of skin. The exact cause is unknown, but skin injury may be a risk factor.

Symptoms of dermatofibrosarcoma protuberans

  • Lumps under the skin

  • Black/blue/brown spots or moles, on the skin and lining of the mouth

Questions your doctor may ask to check for dermatofibrosarcoma protuberans

Your doctor may ask these questions to diagnose dermatofibrosarcoma protuberans

  • Do you feel a lump/lumps under your skin?

  • Are there black, blue, or brown spots on the skin or elsewhere? (Including moles)

Treatment for dermatofibrosarcoma protuberans

Treatment options involves surgery to remove the tumour, radiation therapy or targeted therapy .

View the symptoms of Dermatofibrosarcoma protuberans

Diseases related to Dermatofibrosarcoma protuberans


  • Allen A, Ahn C, Sangüeza OP. Dermatofibrosarcoma Protuberans. Dermatol Clin. 2019 Oct;37(4):483-488. doi: 10.1016/j.det.2019.05.006. PMID: 31466588.

  • Thway K, Noujaim J, Jones RL, Fisher C. Dermatofibrosarcoma protuberans: pathology, genetics, and potential therapeutic strategies. Ann Diagn Pathol. 2016 Dec;25:64-71. doi: 10.1016/j.anndiagpath.2016.09.013. Epub 2016 Sep 27. PMID: 27806849.

  • Mujtaba B, Wang F, Taher A, Aslam R, Madewell JE, Spear R, Nassar S. Dermatofibrosarcoma Protuberans: Pathological and Imaging Review. Curr Probl Diagn Radiol. 2021 Mar-Apr;50(2):236-240. doi: 10.1067/j.cpradiol.2020.05.011. Epub 2020 Jun 1. PMID: 32620358.

  • Badhey AK, Tikhtman R, Tang AL. Management of dermatofibrosarcoma protuberans. Curr Opin Otolaryngol Head Neck Surg. 2021 Aug 1;29(4):278-282. doi: 10.1097/MOO.0000000000000721. PMID: 33993132.

Reviewed By:

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

From our team of 50+ doctors

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Developed by doctors.

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