Dermatofibrosarcoma Protuberans Quiz
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There is a lump
Skin has moles or spots of different colors
Lumps under skin
Black, blue, or brown spots on the skin or elsewhere
Cysts under skin
Discolored macules or moles on skin/mucus membranes
There is a nodule in the groin
Not seeing your symptoms? No worries!
What is Dermatofibrosarcoma Protuberans?
This is an extremely rare skin cancer. It grows slowly and seldom spreads beyond the skin, but it may recur even after removal. It originates from the connective tissue of the skin's middle layer. The exact cause remains unknown, but skin injury could be a risk factor.
Typical Symptoms of Dermatofibrosarcoma Protuberans
- Skin lumps
- Hard or stiff skin
- Smooth, shiny lump on the skin
- Black/blue/brown spots or moles, on the skin and lining of the mouth
- Reddish-brown hard lumps or bumps on the skin
- Soft lump/s on skin
- Skin problems
Diagnostic Questions for Dermatofibrosarcoma Protuberans
Your doctor may ask these questions to check for this disease:
- Have you noticed any lumps on your skin?
- Have you noticed any hard or stiff areas on your skin?
- Is there a shiny or waxy, pearl-like lump on the skin?
- Are there black, blue, or brown spots on your skin? (Including moles)
- Do you have hard, reddish-brown skin lumps or bumps?
Treatment of Dermatofibrosarcoma Protuberans
Treatment options include surgery to remove the tumor, radiation therapy, or targeted therapy if the cancer has certain characteristics.
Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Diseases Related to Dermatofibrosarcoma Protuberans
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Allen A, Ahn C, Sangüeza OP. Dermatofibrosarcoma Protuberans. Dermatol Clin. 2019 Oct;37(4):483-488. doi: 10.1016/j.det.2019.05.006. PMID: 31466588.
https://www.sciencedirect.com/science/article/abs/pii/S0733863519300488?via%3DihubThway K, Noujaim J, Jones RL, Fisher C. Dermatofibrosarcoma protuberans: pathology, genetics, and potential therapeutic strategies. Ann Diagn Pathol. 2016 Dec;25:64-71. doi: 10.1016/j.anndiagpath.2016.09.013. Epub 2016 Sep 27. PMID: 27806849.
https://www.sciencedirect.com/science/article/abs/pii/S1092913416302647?via%3DihubMujtaba B, Wang F, Taher A, Aslam R, Madewell JE, Spear R, Nassar S. Dermatofibrosarcoma Protuberans: Pathological and Imaging Review. Curr Probl Diagn Radiol. 2021 Mar-Apr;50(2):236-240. doi: 10.1067/j.cpradiol.2020.05.011. Epub 2020 Jun 1. PMID: 32620358.
https://www.sciencedirect.com/science/article/abs/pii/S0363018820301146?via%3DihubBadhey AK, Tikhtman R, Tang AL. Management of dermatofibrosarcoma protuberans. Curr Opin Otolaryngol Head Neck Surg. 2021 Aug 1;29(4):278-282. doi: 10.1097/MOO.0000000000000721. PMID: 33993132.
https://journals.lww.com/co-otolaryngology/Abstract/2021/08000/Management_of_dermatofibrosarcoma_protuberans.10.aspx