Familial amyloid polyneuropathy quiz

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Shohei Harase

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Shohei Harase, MD


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Learn more about Familial amyloid polyneuropathy

Content updated on Jun 1, 2022

What is familial amyloid polyneuropathy?

Familial amyloid polyneuropathy (FAPs) are a group of life-threatening multisystem inherited disorders in which amyloid (abnormal protein that can be deposited in any tissue) deposit in the nerve fibers and around the nerves.

Symptoms related to familial amyloid polyneuropathy

  • Decreased sensation over skin

  • Feel the heart is pounding

  • Numbness anywhere from the knees to the ankles

  • Leg or foot numbness

  • Numbness or abnormal sensation

  • Unable to move both legs

  • Dizziness

  • Weakness in arms or legs

Questions your doctor may ask to check for familial amyloid polyneuropathy

Your doctor may ask these questions to diagnose familial amyloid polyneuropathy

  • Do you feel the sensation on your skin has changed?

  • Do you feel your heart is pounding?

  • Do you have numbness from your knees down (such as ankles)?

  • Do you have numbness in your feet?

  • Do you feel any numbness or change in sensation?

Treatment for familial amyloid polyneuropathy

Pain due to familial amyloid polyneuropathy can be treated with anti-seizure medications, antidepressants, or pain killers including opiate drugs. Almost all amyloid in the bloodstream are made in the liver. Hence, liver transplant may be considered to prevent further amyloid deposits.

View the symptoms of Familial amyloid polyneuropathy

Diseases related to Familial amyloid polyneuropathy


Shohei Harase

Medically Reviewed By:

Shohei Harase, MD


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