Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (Primary Care)
Dr. Nass received dual medical degrees from the David Geffen School of Medicine at UCLA and Charles R. Drew University in Medicine and Science. He completed Family Medicine residency at Ventura County Medical Center with subsequent fellowships at Ventura, University of North Carolina-Chapel Hill, George Washington University, and University of California-Irvine. He holds faculty appointments at Keck School of Medicine of USC, Loma Linda University School of Medicine, and Western University of Health Sciences.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Dec 6, 2024
Following the Medical Content Editorial Policy
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Cold sores
Blister on lip
Genital sores
Mouth blisters
Painful urination
Fever
Swollen lymph nodes in groin
Oral lesions
Sores on private area
Pain in the mouth
Painful blisters on hands
Painful blisters on feet
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Painful blisters caused by herpes simplex virus infection. This can happen on the lips (cold sores) or groin (genital herpes). After the first infection, the virus stays dormant in the body. If the immune system weakens, such as from lack of sleep, the virus can reactivate.
There is no cure for this condition, but it often clears without treatment. The doctor may prescribe creams or pills to speed up healing.
Whitley RJ, Roizman B. Herpes simplex virus infections. Lancet. 2001 May 12;357(9267):1513-8. doi: 10.1016/S0140-6736(00)04638-9. PMID: 11377626.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(00)04638-9/fulltextWidener RW, Whitley RJ. Herpes simplex virus. Handb Clin Neurol. 2014;123:251-63. doi: 10.1016/B978-0-444-53488-0.00011-0. PMID: 25015489.
https://www.sciencedirect.com/science/article/abs/pii/B9780444534880000110?via%3DihubJames SH, Kimberlin DW. Neonatal Herpes Simplex Virus Infection. Infect Dis Clin North Am. 2015 Sep;29(3):391-400. doi: 10.1016/j.idc.2015.05.001. Epub 2015 Jul 4. PMID: 26154662.
https://www.sciencedirect.com/science/article/abs/pii/S0891552015000483?via%3DihubFatahzadeh M, Schwartz RA. Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol. 2007 Nov;57(5):737-63; quiz 764-6. doi: 10.1016/j.jaad.2007.06.027. PMID: 17939933.
https://www.jaad.org/article/S0190-9622(07)01045-6/fulltextSamies NL, James SH, Kimberlin DW. Neonatal Herpes Simplex Virus Disease: Updates and Continued Challenges. Clin Perinatol. 2021 Jun;48(2):263-274. doi: 10.1016/j.clp.2021.03.003. PMID: 34030813.
https://www.sciencedirect.com/science/article/abs/pii/S0095510821000166?via%3DihubMale, 30s
I got more answers in one minute through your site than I did in three hours with Google.
(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
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Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
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Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (Primary Care)
Dr. Nass received dual medical degrees from the David Geffen School of Medicine at UCLA and Charles R. Drew University in Medicine and Science. He completed Family Medicine residency at Ventura County Medical Center with subsequent fellowships at Ventura, University of North Carolina-Chapel Hill, George Washington University, and University of California-Irvine. He holds faculty appointments at Keck School of Medicine of USC, Loma Linda University School of Medicine, and Western University of Health Sciences.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
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Link to full study:
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