Herpes Simplex Quiz

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Reviewed By:

Scott Nass

Scott Nass, MD, MPA, FAAFP, AAHIVS (GP / Family doctor)

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

From our team of 50+ doctors

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Learn more about Herpes simplex

Content updated on Sep 20, 2022

What is herpes simplex?

Painful blisters due to infection by the herpes simplex virus. This condition can occur on the lips (cold sores) or groin (genital herpes). After the first bout of infection, the virus lies dormant in the body. If the immune system is weakened e.g. due to lack of sleep, the virus can reactivate.

Symptoms of herpes simplex

  • Skin abnormality

  • Blisters

  • History of herpes

  • Blisters in my lips or mouth

  • Facial pain

  • Small, painful blisters

  • Mental stress or physical exhaustion

  • Decreased urine volume with painful urination

Questions your doctor may ask to check for herpes simplex

Your doctor may ask these questions to diagnose herpes simplex

  • Do you have any skin problems?

  • Do you have blisters on your skin?

  • Have you had herpes (oral or genital) or herpes related disease?

  • Do you have many sores on your lips or in the inside of your mouth?

  • Do you have pain in the face?

Treatment for herpes simplex

There is no cure for this condition, but it often clears without treatment. The doctor may prescribe creams or pills to speed up healing.

View the symptoms of Herpes simplex


  • Whitley RJ, Roizman B. Herpes simplex virus infections. Lancet. 2001 May 12;357(9267):1513-8. doi: 10.1016/S0140-6736(00)04638-9. PMID: 11377626.


  • Widener RW, Whitley RJ. Herpes simplex virus. Handb Clin Neurol. 2014;123:251-63. doi: 10.1016/B978-0-444-53488-0.00011-0. PMID: 25015489.


  • James SH, Kimberlin DW. Neonatal Herpes Simplex Virus Infection. Infect Dis Clin North Am. 2015 Sep;29(3):391-400. doi: 10.1016/j.idc.2015.05.001. Epub 2015 Jul 4. PMID: 26154662.


  • Fatahzadeh M, Schwartz RA. Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol. 2007 Nov;57(5):737-63; quiz 764-6. doi: 10.1016/j.jaad.2007.06.027. PMID: 17939933.


  • Samies NL, James SH, Kimberlin DW. Neonatal Herpes Simplex Virus Disease: Updates and Continued Challenges. Clin Perinatol. 2021 Jun;48(2):263-274. doi: 10.1016/j.clp.2021.03.003. PMID: 34030813.


Reviewed By:

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

From our team of 50+ doctors

Just 3 minutes.
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Kameda Medical Center, Japan

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Emergency department

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Yu Shirai

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Yotsuya Yui Clinic, Japan

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Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

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Rohini R, MD

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Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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