Juvenile Myoclonic Epilepsy (Janz Syndrome) Quiz
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Limb spasms on one side in the morning when waking up
Faint when I lack of sleep
Syncope when I drink alcohol
Right hand and leg jerks when I am about to wake up
Right hand and leg jerks for a while after I wake up
Limb spasms on one side especially just after I wake up
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Try Free Symptom QuizWhat is Juvenile Myoclonic Epilepsy (Janz Syndrome)?
Juvenile myoclonic epilepsy (Janz syndrome) is an epilepsy syndrome marked by the presence of absence, myoclonic, and generalized tonic-clonic (GTC) seizures. All patients with JME have myoclonic seizures, 85%-90% of patients have generalized tonic-clonic seizures, and about 20-40% of patients have absence seizures. These often happen when people first wake up in the morning. The exact cause is unknown, but a family history of epilepsy or gene mutations may sometimes be connected to the condition.
Treatment of Juvenile Myoclonic Epilepsy (Janz Syndrome)
Juvenile myoclonic epilepsy (Janz syndrome) is typically well managed with medications for seizures. Most patients don't outgrow their seizures and will need to take medication for the rest of their lives. Getting enough sleep, avoiding alcohol, fatigue and anxiety can help lower the chances of seizures.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
Content updated on Apr 4, 2024
Following the Medical Content Editorial Policy
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Juvenile Myoclonic Epilepsy (Janz Syndrome)?
Try a symptom check testDiseases Related to Juvenile Myoclonic Epilepsy (Janz Syndrome)
References
Bittermann HJ, Steinhoff BJ. Die juvenile myoklonische Epilepsie (Janz-Syndrome). Ein gut bekanntes Epilepsiesyndrom? [Juvenile myoclonic epilepsy (Janz syndrome). A well-known epilepsy syndrome?]. Nervenarzt. 1998 Feb;69(2):127-30. German. doi: 10.1007/s001150050248. PMID: 9551456.
https://pubmed.ncbi.nlm.nih.gov/9551456/#:~:text=Juvenile%20myoclonic%20epilepsy%20(JME)%20was,deprivation%2C%20alcohol%20consumption%20and%20flickeringAmrutkar CV, Riel-Romero RM. Juvenile Myoclonic Epilepsy. [Updated 2023 Feb 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537109/
https://www.ncbi.nlm.nih.gov/books/NBK537109/#:~:text=Juvenile%20myoclonic%20epilepsy%20(JME)%2C,Lund%20in%201975%20as%20JME.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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