Sydenham Chorea Quiz

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Reviewed By:

Benjamin Kummer, MD

Benjamin Kummer, MD (Neurology)

Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

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Content updated on Mar 31, 2024

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How Ubie Can Help You

With an easy 3-min questionnaire , Ubie's AI-powered system will generate a free report on possible causes.

Questions are customized to your situation and symptoms, including the following personal information:

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People with similar symptoms also use Ubie's symptom checker to find possible causes

  • Drowsy

  • Abnormal gait

  • Does not respond to instructions

  • Slow twitching of arms and legs

  • Act weird

  • Essential tremor

  • Response is slower than usual

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What is Sydenham Chorea?

Sydenham chorea is a rare neurological disorder characterized by sudden onset abnormal movements that occur after infection with group A streptococcus bacteria. Most people are affected during childhood. Movements are random, continuous, and involuntary, sometimes affecting the entire body. The disease is thought to occur because antibodies against group A streptococcus cross-react with nerve cells in the basal ganglia, a structure in the brain that fine-tunes voluntary movements.

Typical Symptoms of Sydenham Chorea

  • Abnormal behavior

  • Uncontrollable movements

  • Difficulty in walking

  • Slurred speech

  • Fine tremor of the hands and fingers

Doctor's Diagnostic Questionson Sydenham Chorea

Your doctor may ask these questions to check for this disease:

  • Have you noticed or been told that you are acting strangely or differently lately?

  • Do you have uncontrollable movements in your hands, legs, or face?

  • Is walking difficult for you?

  • Is your speech slurred?

  • Do your fingers tremble slightly?

Treatmentof Sydenham Chorea

Treatment of Sydenham chorea includes antibiotics against group A streptococcus, antipsychotic and anti-seizure medications to control movements, or medications to reduce the activity of the immune system.

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References

  • Oosterveer DM, Overweg-Plandsoen WC, Roos RA. Sydenham's chorea: a practical overview of the current literature. Pediatr Neurol. 2010 Jul;43(1):1-6. doi: 10.1016/j.pediatrneurol.2009.11.015. PMID: 20682195.

    https://www.pedneur.com/article/S0887-8994(10)00035-4/fulltext

  • Karalok ZS, Öztürk Z, Gunes A, Gurkas E. Sydenham Chorea: Putaminal Enlargement. J Child Neurol. 2021 Jan;36(1):48-53. doi: 10.1177/0883073820951364. Epub 2020 Aug 27. PMID: 32851928.

    https://journals.sagepub.com/doi/10.1177/0883073820951364

  • Tariq S, Niaz F, Waseem S, Shaikh TG, Ahmed SH, Irfan M, Nashwan AJ, Ullah I. Managing and treating Sydenham chorea: A systematic review. Brain Behav. 2023 Jun;13(6):e3035. doi: 10.1002/brb3.3035. Epub 2023 May 7. PMID: 37150977; PMCID: PMC10275551.

    https://onlinelibrary.wiley.com/doi/10.1002/brb3.3035

  • Depietri G, Carli N, Sica A, Oliviero D, Costagliola G, Striano P, Bonuccelli A, Frisone F, Peroni D, Consolini R, Foiadelli T, Orsini A. Therapeutic aspects of Sydenham's Chorea: an update. Acta Biomed. 2022 Mar 21;92(S4):e2021414. doi: 10.23750/abm.v92iS4.12663. PMID: 35441610; PMCID: PMC9179053.

    https://mattioli1885journals.com/index.php/actabiomedica/article/view/12663

User Testimonials

Reviewed By:

Benjamin Kummer, MD

Benjamin Kummer, MD (Neurology)

Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

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