Sydenham Chorea Quiz

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Unusual behavior

Hard to walk

Uncontrolled movements

Speech not fluent

Hands have fine tremors

Acting out of character

Involuntary movements

Not seeing your symptoms? No worries!

What is Sydenham Chorea?

Sydenham chorea is a rare neurological disorder characterized by sudden onset abnormal movements that occur after infection with group A streptococcus bacteria. Most people are affected during childhood. Movements are random, continuous, and involuntary, sometimes affecting the entire body. The disease is thought to occur because antibodies against group A streptococcus cross-react with nerve cells in the basal ganglia, a structure in the brain that fine-tunes voluntary movements.

Typical Symptoms of Sydenham Chorea

Diagnostic Questions for Sydenham Chorea

Your doctor may ask these questions to check for this disease:

  • Do you have uncontrollable movements in your hands, legs, or face?
  • Have you noticed or been told that you are acting strangely or differently?
  • Do you have difficulty walking normally?
  • Are you having difficulty speaking clearly?
  • Do you experience fine tremors in your hands or fingers?

Treatment of Sydenham Chorea

Treatment of Sydenham chorea includes antibiotics against group A streptococcus, antipsychotic and anti-seizure medications to control movements, or medications to reduce the activity of the immune system.

Reviewed By:

Benjamin Kummer, MD

Benjamin Kummer, MD (Neurology)

Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

From our team of 50+ doctors

Content updated on Mar 31, 2024

Following the Medical Content Editorial Policy

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Link to full study:

https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1

References