Twin-to-Twin Transfusion Syndrome Quiz

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Reviewed By:

Ravi P. Chokshi, MD

Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)

Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.

Seiji Kanazawa, MD, PHD

Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))

Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.

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Content updated on Mar 31, 2024

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What is Twin-to-Twin Transfusion Syndrome?

Twin-to-twin transfusion syndrome (TTTS) is a rare condition that only occurs in pregnancies with identical twins where they share a placenta. The placenta is the organ that provides blood supply from the mom to both babies. In TTTS, there is unequal blood supply with one twin getting more blood than the other. One twin, the donor twin, gives away more blood than it receives, leading to a risk of malnourishment, poor growth and organ failure. The other twin (recipient) receives too much blood, which can cause the heart to be overworked and lead to other cardiac complications. In this condition both twins are at risk for stillbirth and poor outcome, and these pregnancies are considered high risk.

Typical Symptoms of Twin-to-Twin Transfusion Syndrome

  • Diagnosis of Monochorionic twins

  • Diagnosed with multiple pregnancy (twins or more)

  • Rapid increase in abdominal circumference (waist size)

  • Feel my child is moving less. (Decreased fetal movements)

  • Currently pregnant

  • Stomach feels constantly hard and stiff like a board

  • Feeling contractions very frequently

  • Increased vaginal discharge that is smelly

Doctor's Diagnostic Questionson Twin-to-Twin Transfusion Syndrome

Your doctor may ask these questions to check for this disease:

  • Have you been told that you have Monochorionic twins?

  • Are you carrying more than one fetus?

  • Has your waist size increased quickly recently?

  • Is your child moving less?

  • Are you pregnant?

Treatmentof Twin-to-Twin Transfusion Syndrome

In twin pregnancies that share a placenta, ultrasound examinations are frequently done to monitor for this condition. These pregnancies need a lot of monitoring and specialist care. If TTTS is detected, fetal laser therapy may be considered to divide the blood supply between the twins.

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Diseases related to Twin-to-Twin Transfusion Syndrome

References

  • Yoda H. Fetal and Neonatal Circulatory Disorders in Twin to Twin Transfusion Syndrome (The Secondary Publication). J Nippon Med Sch. 2019;86(4):192-200. doi: 10.1272/jnms.JNMS.2019_86-301. PMID: 31484880.

    https://www.jstage.jst.go.jp/article/jnms/86/4/86_JNMS.2019_86-301/_article

  • Twin-Twin Transfusion Syndrome

    https://www.smfm.org/publications/80-twin-twin-transfusion-syndrome

  • Twin-to-Twin Transfusion Syndrome

    https://www.ncbi.nlm.nih.gov/books/NBK563133/

User Testimonials

Reviewed By:

Ravi P. Chokshi, MD

Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)

Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.

Seiji Kanazawa, MD, PHD

Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))

Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.

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