Watery Diarrhea, Hypokalemia, and Achlorhydria (WDHA) Syndrome Quiz
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Scott Nass, MD, MPA, FAAFP, AAHIVS (GP / Family doctor)
Yoshinori Abe, MD (Internal medicine)
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Learn more about Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Content updated on Sep 20, 2022
What is watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome?
WDHA (watery diarrhea, hypokalemia, and achlorhydria) syndrome is an unusual condition caused by excess vasoactive intestinal polypeptide (VIP) secreted by certain tumors. VIP is a neuromodulator and neurotransmitter. It dilates blood vessels, regulates smooth muscle activity, cell secretion and blood flow in the gastrointestinal tract.
Symptoms of watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Fatigue
Diarrhea
Recent weight loss
Loss of appetite
Weakness in arms or legs
Facial flushing
Feel the heart is pounding
Questions your doctor may ask to check for watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Your doctor may ask these questions to diagnose watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Do you feel fatigued?
Do you have loose stools or diarrhea?
Have you lost weight recently?
Do you have less or no appetite, therefore eat less food?
Do you feel any weakness in your arms or legs?
Treatment for watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Treatment includes correction of blood volume, electrolytes, and metabolic abnormalities, and medication to decrease gastrointestinal secretion and increase absorption. Surgical removal of the tumor is also required.
View the symptoms of Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Diseases related to Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (GP / Family doctor)
Yoshinori Abe, MD (Internal medicine)
Just 3 minutes.
Developed by doctors.
Ubie is supervised by 50+ medical experts worldwide
Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan