Watery Diarrhea, Hypokalemia, and Achlorhydria (WDHA) Syndrome Quiz
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Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (Primary Care Physician)
Dr. Nass received dual medical degrees from the David Geffen School of Medicine at UCLA and Charles R. Drew University in Medicine and Science. He completed Family Medicine residency at Ventura County Medical Center with subsequent fellowships at Ventura, University of North Carolina-Chapel Hill, George Washington University, and University of California-Irvine. He holds faculty appointments at Keck School of Medicine of USC, Loma Linda University School of Medicine, and Western University of Health Sciences.
Yoshinori Abe, MD (Internal medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
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Easily tired
Fatigue that varies throughout the day
Constipation and diarrhea
Fatigue is worse in the morning
Symptoms worse at the end of the day
Losing too much weight
Diarrhea throughout the whole day
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Learn more about Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Content updated on Sep 20, 2022
What is watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome?
WDHA syndrome, which stands for watery diarrhea, hypokalemia, and achlorhydria, is a rare condition caused by an excess of vasoactive intestinal polypeptide (VIP) secreted by certain tumors. VIP is both a neuromodulator and a neurotransmitter that dilates blood vessels, regulates smooth muscle activity, cell secretion, and blood flow in the gastrointestinal tract.
Symptoms of watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Fatigue
Diarrhea
Recent weight loss
Loss of appetite
Weakness in arms or legs
Facial flushing
Feel the heart is pounding
Questions your doctor may ask to check for watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Your doctor may ask these questions to diagnose watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Do you feel fatigued?
Do you have loose stools or diarrhea?
Have you lost weight recently?
Do you have less or no appetite, therefore eat less food?
Do you feel any weakness in your arms or legs?
Treatment for watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Treatment involves correcting blood volume, electrolytes, and metabolic abnormalities, as well as using medication to decrease gastrointestinal secretion and increase absorption. Surgical removal of the tumor is also necessary.
View the symptoms of Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
Diseases related to Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
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Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (Primary Care Physician)
Dr. Nass received dual medical degrees from the David Geffen School of Medicine at UCLA and Charles R. Drew University in Medicine and Science. He completed Family Medicine residency at Ventura County Medical Center with subsequent fellowships at Ventura, University of North Carolina-Chapel Hill, George Washington University, and University of California-Irvine. He holds faculty appointments at Keck School of Medicine of USC, Loma Linda University School of Medicine, and Western University of Health Sciences.
Yoshinori Abe, MD (Internal medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Just 3 minutes.
Developed by doctors.
Ubie is supervised by 50+ medical experts worldwide
Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan