Our Services
Medical Information
Helpful Resources
Published on: 7/21/2026
What type of exercise helps with GLP-1 muscle wasting?
Muscle loss is a common side effect of GLP-1 medications like Ozempic and Wegovy, but resistance training can help protect and preserve lean muscle mass. Activities such as weightlifting, bodyweight exercises (squats, push-ups, lunges), and resistance band workouts stimulate muscle growth and counteract the muscle-wasting effects of rapid weight loss. Experts recommend strength training at least 2–3 times per week, paired with adequate protein intake, to maintain strength, metabolism, and overall body composition while on GLP-1 therapy.
If you're experiencing muscle weakness, fatigue, or other symptoms while taking a GLP-1 medication, it's worth investigating the root cause before making changes to your routine. Taking a free, instant, online symptom check can help you better understand what's going on in your body and guide your next steps—whether that means adjusting your exercise plan, consulting your doctor, or exploring other health concerns. It only takes a few minutes and could give you valuable clarity.
Reviewed for medical accuracy: 07/20/2026
Important Next Steps
Not seeing your question? No worries.
Submit your own QuestionExplanation
When using GLP-1 medications, some people may experience muscle loss. To help with this, resistance exercises, such as lifting weights, are recommended. These exercises can help build and maintain muscle strength.
Why Resistance Exercise?
- Builds Muscle: Resistance training involves activities like lifting weights or using resistance bands. This type of exercise helps increase muscle mass and strength.
- Prevents Muscle Loss: Regular resistance exercise can help prevent the muscle loss that may occur with GLP-1 medication use.
Tips for Starting:
- Start Slow: If you are new to resistance training, begin with lighter weights and gradually increase as you become stronger.
- Consistency is Key: Aim to do resistance exercises at least 2-3 times a week.
- Mix It Up: Include exercises that target different muscle groups to ensure balanced muscle development.
Always consult with a healthcare provider or a fitness professional before starting any new exercise program, especially if you have underlying health conditions. If you're experiencing any concerning symptoms, take our free symptom checker to better understand what might be happening with your body.
(References)
Locatelli JC, Costa JG, Haynes A, Naylor LH, Fegan PG, Yeap BB, & Green DJ. (2024). Incretin-Based Weight Loss Pharmacotherapy. Diabetes care, 38687506.
Mechanick JI, Butsch WS, Christensen SM, Hamdy O, Li Z, Prado CM, & Heymsfield SB. (2025). Strategies for minimizing muscle loss during use of incretin .... Obesity reviews : an official journal of the International Association for the Study of Obesity, 39295512.
Grosicki GJ, Dhurandhar NV, Unick JL, Arent SM, Thomas JG, Lofton H, et al. (2024). The Importance of Diet and Physical Activity to Support .... Current developments in nutrition, 39624804.
Tell your friends about us.
We would love to help them too.
For First Time Users
What is Ubie’s Doctor’s Note?
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.