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Published on: 7/24/2025

Can GLP-1 drugs affect physical function due to muscle loss?

GLP-1 drugs can lead to muscle loss, which may affect physical function, but there are strategies to minimize this risk.

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Explanation

GLP-1 drugs, used for diabetes and weight management, can sometimes cause a decrease in muscle mass. This is important because muscles help us move and do everyday activities.

Effects on Muscle Mass:

  • While GLP-1 drugs can reduce body weight, they may also lead to a reduction in lean body mass, which includes muscles.

Strategies to Minimize Muscle Loss:

  • Strategies have been suggested to reduce muscle loss while using these medications. These include regular exercise and ensuring adequate protein intake, which can help maintain muscle strength.

Considerations for Older Adults:

  • The importance of monitoring muscle health has been discussed, especially in older adults who may be more prone to frailty. Ensuring safety and minimizing risks is crucial when using these medications.

Overall, while GLP-1 drugs can be helpful, it is important to focus on maintaining muscle health through lifestyle choices and regular check-ups with healthcare providers.

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