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Published on: 8/20/2026

What can cause pain when pressing on the inside of the knee?

Pain when pressing on the inside of the knee is often caused by inflammation or irritation of soft tissues in that area. Common causes include pes anserine bursitis (irritation of the fluid-filled sac below the inner knee) and saphenous neuritis (irritation of the saphenous nerve). Other possible causes include a medial meniscus injury, MCL strain, or medial compartment osteoarthritis.

Because inner knee pain can stem from several different conditions—each requiring a different approach to treatment—it's important to narrow down the likely cause before deciding on next steps. A free, instant, online symptom check can help you identify potential causes based on your specific symptoms, guide you on when to see a doctor, and help you prepare for that visit with clearer information. Taking a few minutes now can save you time, worry, and unnecessary guesswork.

Reviewed for medical accuracy: 07/15/2026

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When you press on the inside of your knee, it might hurt because the soft tissues in that area are irritated. One common cause is pes anserine bursitis. This happens when a small, fluid-filled sac called a bursa, which sits near where three tendons come together on the inner knee, gets swollen and inflamed. Another possible cause is saphenous neuritis, where the saphenous nerve, a small nerve running along the inside of your knee, becomes irritated, leading to pain. Other possibilities can include issues with the medial collateral ligament (MCL) or a tear in the meniscus, but these usually hurt more than just tenderness only on pressing. In simple terms, sometimes the pain is like a red, swollen spot that gets sore when touched because a part of the knee is dealing with irritation from overuse or injury. To help identify what might be causing your specific knee pain, try our free AI symptom checker for personalized insights based on your symptoms.

(References)

  • Lerew S, Stoker S, Nallamothu S. The Rules of Four: A Systematic Approach to Diagnosing Common Musculoskeletal Conditions of the Knee. Spartan Med Res J. 2020 Jan 30;4(2):11765. doi: 10.51894/001c.11765. PMID: 33655173; PMCID: PMC7746119.

  • Duong V, Oo WM, Ding C, Culvenor AG, Hunter DJ. Evaluation and Treatment of Knee Pain: A Review. JAMA. 2023 Oct 24;330(16):1568-1580. doi: 10.1001/jama.2023.19675. PMID: 37874571.

  • Morganti CM, McFarland EG, Cosgarea AJ. Saphenous neuritis: a poorly understood cause of medial knee pain. J Am Acad Orthop Surg. 2002 Mar-Apr;10(2):130-7. doi: 10.5435/00124635-200203000-00008. PMID: 11929207.

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