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Published on: 11/26/2025

Can sleep medications lose effectiveness over time?

Yes, sleep medications can lose effectiveness over time because the body can get used to them.

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Explanation

Sleep medications, like antihistamines and benzodiazepines, can become less effective over time. This happens because the body can develop a tolerance, meaning you might need more of the medication to get the same effect.

Types of Sleep Medications:

  1. Antihistamines:

    • These are often used for allergies but can also help with sleep. Over time, the body can get used to them, and they might not work as well for making you sleepy.
  2. Benzodiazepines:

    • These are a type of medication that can help with anxiety and sleep. People can develop a tolerance to these quickly, sometimes even after just a short time of use.
  3. Non-benzodiazepines:

    • These are newer sleep medications. They are less likely to cause tolerance, but it can still happen.

If you are having trouble with sleep medications not working well, it is important to talk to a doctor. They can help find a solution that is safe and works for you. For mental health support, visit 988lifeline.org.

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