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Published on: 4/7/2025

What Are the Treatment Options for Toenail Discoloration?

Toenail discoloration can be treated in several ways, especially if it is caused by a fungal infection. Options include topical treatments, oral medications, and sometimes device-based therapies or nail care procedures.

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Explanation

When toenails change color, it can sometimes mean there is a fungal infection called onychomycosis. To treat this, doctors might suggest using antifungal creams, solutions, or lacquers that you put on your toenails every day. These are called topical treatments. Sometimes, if the infection is deep or worse, you might be given an antifungal pill that works from the inside; examples include terbinafine or itraconazole. In addition, some newer treatments use lasers or light-based devices to help kill the fungus. Apart from medications, keeping your toenails clean, trimmed, and dry is very important during treatment. There are also procedures like nail debridement, where a professional cleans out thick or discolored parts of the nail. Each option works in different ways, and the best treatment depends on the severity of the discoloration and other factors like your overall health. It’s important to work with your doctor to choose the treatment that is best for you, and to remember that treating toenail fungus can take several months of care.

(References)

  • Finch JJ, Warshaw EM. Toenail onychomycosis: current and future treatment options. Dermatol Ther. 2007 Jan-Feb;20(1):31-46. doi: 10.1111/j.1529-8019.2007.00109.x. PMID: 17403258.

  • Falotico JM, Lipner SR. Updated Perspectives on the Diagnosis and Management of Onychomycosis. Clin Cosmet Investig Dermatol. 2022 Sep 15;15:1933-1957. doi: 10.2147/CCID.S362635. PMID: 36133401; PMCID: PMC9484770.

  • Yousefian F, Smythe C, Han H, Elewski BE, Nestor M. Treatment Options for Onychomycosis: Efficacy, Side Effects, Adherence, Financial Considerations, and Ethics. J Clin Aesthet Dermatol. 2024 Mar;17(3):24-33. PMID: 38495549; PMCID: PMC10941855.

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