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Published on: 1/13/2026
Vitamin D can support erectile function in men over 65 by improving endothelial nitric oxide and blood flow; consider supplementing if a 25-hydroxyvitamin D blood test is low, using 50,000 IU D3 weekly for 8–12 weeks when deficient or 1,000–2,000 IU daily if insufficient, with a target of 40–60 ng/mL. There are several factors to consider, including cardiovascular risks, medications, and toxicity limits, so recheck levels after 3–4 months, avoid more than 10,000 IU daily without medical supervision, and pair vitamin D with lifestyle and hormone evaluation; see below for important details that could shape your next steps.
Vitamin D for Erectile Dysfunction in Men Over 65: When Supplementing Makes Sense
Erectile dysfunction (ED) affects a large number of men over age 65 and can stem from multiple causes—including vascular health, hormone levels and lifestyle factors. One often-overlooked piece of the puzzle is vitamin D. In this article you'll learn:
If you're experiencing ED or other troubling symptoms, try Ubie's free AI Erectile Dysfunction Symptom Checker to get personalized insights before you speak to your doctor.
Vitamin D is best known for bone health, but it also:
Healthy erections depend on good blood flow through the penile arteries. Vitamin D helps the inner lining of blood vessels (the endothelium) produce nitric oxide, a key molecule that relaxes smooth muscle and allows blood to fill the penis. Low vitamin D can therefore contribute to poor vascular health and, over time, to ED.
Several studies link vitamin D status to endothelial and erectile function:
• Tarcin et al. (2009) showed men with low vitamin D had worse endothelial function; after 12 weeks of high-dose vitamin D replacement, endothelial performance improved significantly.
• Observational data reveal that men with ED often have lower 25-hydroxyvitamin D levels than those without ED. The severity of ED tends to correlate inversely with vitamin D status: the lower the level, the worse the symptoms.
• Deficient vitamin D is associated with higher rates of cardiovascular disease and diabetes—both major risk factors for ED in older men.
Testing makes sense when:
A simple blood test (serum 25-hydroxyvitamin D) will let you know if your level is:
• Deficiency (below 20 ng/mL)
– High-dose replacement can correct levels quickly
– Typical regimen: 50,000 IU vitamin D3 once weekly for 8–12 weeks, then reassess
• Insufficiency (20–30 ng/mL)
– Daily maintenance dosing often works well
– Typical regimen: 1,000–2,000 IU vitamin D3 daily
• Sufficiency (above 30 ng/mL)
– Continue a moderate maintenance dose if risk factors persist
– Aim to keep levels in the 40–60 ng/mL range for optimal vascular support
Vitamin D toxicity is rare but can occur with very high, prolonged doses. Symptoms include:
To avoid toxicity:
While vitamin D may improve endothelial function, ED is often multi-factorial. Consider also:
ED can sometimes signal serious health issues, including heart disease. If you notice:
…you should immediately seek medical evaluation or call emergency services. For non-emergent questions, always "speak to a doctor" about any treatments, dosing changes or if symptoms persist despite lifestyle and supplement efforts.
Always remember: while vitamin D may support erectile and vascular health, ED can be a sign of underlying conditions that require professional care. Speak to a doctor about any life-threatening or serious concerns, and before starting or changing any supplement or medication regimen.
(References)
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. (2011). Evaluation, treatment, and prevention of vitamin D defici… J Clin Endocrinol Metab, 21188120.
Tarcin O, Yavuz DG, Ozben B, et al. (2009). Effect of vitamin D deficiency and replacement on endothe… J Clin Endocrinol Metab, 18678623.
European Association for the Study of the Liver. (2018). EASL clinical practice guidelines for the management of pa… Journal of Hepatology, 29459475.
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