Adult Still's Disease Quiz
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Have a fever
Redness of the skin
Have joint pain
Joint pain that is always there
Sore throat
Lymph swollen
Upper jaw hurts
Not seeing your symptoms? No worries!
What is Adult Still's Disease?
A rare systemic inflammatory disease characterized by high fevers, a pink rash, sore throat and body aches that persist for weeks. The exact cause is unknown but is thought to be triggered by an infection. Some patients will have only one episode of it, while others may have several recurrent episodes.
Typical Symptoms of Adult Still's Disease
- Fever above 100.4°F / 38°C lasting 7 days or longer
- Fever
- Multiple areas of skin redness or red spots
- Recurrent fever episodes
- Swollen lymph nodes or lumps in the neck, armpits, groin, or behind the ears
- Multiple swollen lymph nodes or lumps in neck or armpits
- Joint pain, swelling, or discomfort
- Warmth in the joints
Diagnostic Questions for Adult Still's Disease
Your doctor may ask these questions to check for this disease:
- Have you had a fever above 100.4°F / 38°C for 7 days or longer?
- Do you have a fever?
- Do you have multiple red areas or spots on your skin?
- Do you have recurrent fever episodes?
- Do you have any swollen lymph nodes or lumps in your neck, armpits, groin, or behind your ears?
Treatment of Adult Still's Disease
It is typically treated with medicine to reduce inflammation and pain. It may also require steroids or medications that dampen the body's immune response.
Reviewed By:
Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.
Kaito Nakamura, MD (Rheumatology)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Content updated on Feb 19, 2025
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- My body is hot
- Recurrent fevers
- Periodic fever (>100.4°F / 38°C)
- Swollen lymph nodes above collar bone
- Fever then no fever then fever again
- Remittent fever of 102.2°F / 39°C
- Extremely high fever of 106.7°F / 41.5°C or higher
- Swollen armpit
- Fever of 100.4°F / 38°C or more for weeks
- Stomach was uncomfortable, then had a fever
- Swollen lymph nodes continue to grow larger
- Stomachache and diarrhea before a fever
- Temperature of 102.2°F / 39°C goes up and down
- It moves when I touch the lump
- Multiple lymph nodes swollen in my groin
See full list
Symptoms Related to Adult Still's Disease
Diseases Related to Adult Still's Disease
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Leavis HL, van Daele PLA, Mulders-Manders C, Michels R, Rutgers A, Legger E, Bijl M, Hak EA, Lam-Tse WK, Bonte-Mineur F, Fretter P, Simon A, van Paassen P, van der Goes MC, Flendrie M, Vercoutere W, van Lieshout AWT, Leek A, Vastert SJ, Tas SW (2021). Management of adult-onset Still's disease: evidence- and consensus-based recommendations by experts. Rheumatology (Oxford, England).
https://pubmed.ncbi.nlm.nih.gov/37669122/Tomaras S, Goetzke CC, Kallinich T, Feist E (2021). Adult-Onset Still's Disease: Clinical Aspects and Therapeutic Approach. Journal of clinical medicine.
https://pubmed.ncbi.nlm.nih.gov/33673234/Gerfaud-Valentin M, Jamilloux Y, Iwaz J, Sève P (2014). Adult-onset Still's disease. Autoimmunity reviews.
https://pubmed.ncbi.nlm.nih.gov/24657513/