Arteriosclerosis Obliterans Quiz
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Loss of sensation
Leg pain
Walking causes legs to tingle but it gets better after rest
Tingling
Pain in legs when walking/taking stairs
Numbness in lower leg
My arm and leg on one side is harder to move than the other
Not seeing your symptoms? No worries!
What is Arteriosclerosis Obliterans?
Arteriosclerosis obliterans or peripheral artery disease is a condition where arteries become clogged from fatty deposits. The most commonly affected arteries are the abdominal aorta and arteries of the lower limbs. Common symptoms include pain and cramping in the lower extremities with increased activity because those muscles are unable to get adequate blood flow.
Typical Symptoms of Arteriosclerosis Obliterans
- Tingling or pricking numbness or pain in the legs that improves after a period of rest
- Numbness anywhere from the knees to the ankles
- Fingers and toes are pale white or blue
- Bluish or pale skin
- Cold hands and feet
- Kidney failure on dialysis
- Decreased sensation over skin
- Numbness or tingling
Diagnostic Questions for Arteriosclerosis Obliterans
Your doctor may ask these questions to check for this disease:
- Are you able to exercise again after your pain and numbness improve with rest?
- Do you have numbness in your lower legs?
- Are your fingers or toes pale?
- Do you have any bluish or pale skin?
- Do you often have cold hands and feet?
Treatment of Arteriosclerosis Obliterans
Treatment for arteriosclerosis obliterans first and foremost involves risk reduction through diet, exercise, smoking cessation and treatment of commonly co-occurring diseases like high blood pressure, high cholesterol and diabetes with medications. For more severe disease, treatment involves medications to prevent blood clots and ease symptoms. Surgery may be done to open up the blocked arteries.
Reviewed By:
Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.
Kaito Nakamura, MD (Rheumatology)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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- Numbness in fingers
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- Always cold
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Diseases Related to Arteriosclerosis Obliterans
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Sasaki H, Konisi K. [Pathophysiology and diagnosis for arteriosclerosis obliterans]. Rinsho Byori. 2002 Aug;50(8):802-6. Japanese. PMID: 12373817.
https://pubmed.ncbi.nlm.nih.gov/12373817/Ono K. MicroRNA-133a in the Development of Arteriosclerosis Obliterans. J Atheroscler Thromb. 2015;22(4):342-3. doi: 10.5551/jat.ED006. Epub 2015 Feb 27. PMID: 25740337.
https://www.jstage.jst.go.jp/article/jat/22/4/22_ED006/_articleTakahashi K. [Basic research and drug development for arteriosclerosis obliterans]. Nihon Yakurigaku Zasshi. 2007 Nov;130(5):393-7. Japanese. doi: 10.1254/fpj.130.393. PMID: 18000354.
https://www.jstage.jst.go.jp/article/fpj/130/5/130_5_393/_article/-char/ja/SELIGMAN B. Arteriosclerosis obliterans; an epitome. J Am Geriatr Soc. 1959 Feb;7(2):161-6. doi: 10.1111/j.1532-5415.1959.tb01061.x. PMID: 13630689.
https://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.1959.tb01061.x