Chronic Inflammatory Demyelinating Polyneuropathy Quiz
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Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Learn more about Chronic inflammatory demyelinating polyneuropathy
Content updated on Sep 20, 2022
What is chronic inflammatory demyelinating polyneuropathy?
Chronic inflammatory demyelinating polyneuropathy (CIDP) or chronic relapsing polyneuropathy occurs when immune system attacks the myelin sheaths (protective fatty covering) around the nerves. The exact triggers are unclear but could be systemic conditions like liver disease, diabetes, infections, cancer, immune system disorders, etc.
Symptoms of chronic inflammatory demyelinating polyneuropathy
Decreased sensation over skin
Numbness anywhere from the knees to the ankles
Numbness or abnormal sensation
Numbness in the region from shoulder to elbow
Unable to move both arms
Hands and legs became clumsy - I cannot do fine work with them
Weakness in arms or legs
Tingling or prickling sensation of the skin
Questions your doctor may ask to check for chronic inflammatory demyelinating polyneuropathy
Your doctor may ask these questions to diagnose chronic inflammatory demyelinating polyneuropathy
Do you feel the sensation on your skin has changed?
Do you have numbness from your knees down (such as ankles)?
Do you feel any numbness or change in sensation?
Do you have numbness from the shoulder to elbow?
Are you unable to move both arms?
Treatment for chronic inflammatory demyelinating polyneuropathy
Treatment for CIDP includes physiotherapy, steroids, immune-suppressing drugs and intravenous immunoglobulin. Physiotherapy aims to improve function and prevent shrinkage of muscles and tendons.
View the symptoms of Chronic inflammatory demyelinating polyneuropathy
Diseases related to Chronic inflammatory demyelinating polyneuropathy
References
Kuwabara S, Misawa S. Chronic Inflammatory Demyelinating Polyneuropathy. Adv Exp Med Biol. 2019;1190:333-343. doi: 10.1007/978-981-32-9636-7_21. PMID: 31760654.
https://link.springer.com/chapter/10.1007/978-981-32-9636-7_21
Lehmann HC, Burke D, Kuwabara S. Chronic inflammatory demyelinating polyneuropathy: update on diagnosis, immunopathogenesis and treatment. J Neurol Neurosurg Psychiatry. 2019 Sep;90(9):981-987. doi: 10.1136/jnnp-2019-320314. Epub 2019 Apr 16. PMID: 30992333.
https://jnnp.bmj.com/content/90/9/981
Rodríguez Y, Vatti N, Ramírez-Santana C, Chang C, Mancera-Páez O, Gershwin ME, Anaya JM. Chronic inflammatory demyelinating polyneuropathy as an autoimmune disease. J Autoimmun. 2019 Aug;102:8-37. doi: 10.1016/j.jaut.2019.04.021. Epub 2019 May 6. PMID: 31072742.
https://www.sciencedirect.com/science/article/abs/pii/S0896841119300435?via%3Dihub
Muley SA, Jacobsen B, Parry G, Usman U, Ortega E, Walk D, Allen J, Pasnoor M, Varon M, Dimachkie MM. Rituximab in refractory chronic inflammatory demyelinating polyneuropathy. Muscle Nerve. 2020 May;61(5):575-579. doi: 10.1002/mus.26804. Epub 2020 Jan 21. PMID: 31922613.
https://onlinelibrary.wiley.com/doi/10.1002/mus.26804
Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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National Center for Child Health and Development, Japan