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My whole body aches and I feel weak
Body aches and chills
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Whole body aches no fever
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Whole body pain
Pain throughout the body occurs when the muscles, tendons, joints, and other connective tissues hurt. It can be described as sharp, dull, aching, stabbing or throbbing pain.
Seek professional care if you experience any of the following symptoms
Generally, Whole body pain can be related to:
A condition causing widespread pain and muscle aches throughout the body that may come and go with certain identified triggers. The cause is not well understood.
Cancer pain occurs when cancer grows into or invades nearby bone and tissue. As the cancer expands, it can press on surrounding nerves, bones, and organs, causing pain. The tumor can also release chemicals that cause pain.
A disease in which "amyloid," an abnormal type of protein, accumulates in various organs, causing damage. Affected areas can include the heart, kidneys, and gastrointestinal tract. The causes are diverse.
Sometimes, Whole body pain may be related to these serious diseases:
Decompression sickness (also called "the bends") refers to problems caused by a rapid decrease in surrounding pressure (either air or water). This causes gases to dangerously shift out of the bloodstream. It most commonly occurs during scuba diving when surfacing too quickly. Rarely, it can happen in airplanes, typically in military pilots traveling at high speeds through upper and lower atmosphere layers.
Your doctor may ask these questions to check for this symptom:
Reviewed By:
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Content updated on Feb 6, 2025
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Male, 70s
For years, I have experienced chronic pain, deep and radiating throughout my body along with extreme, debilitating fatigue. I have lupus, but thankfully, I have been in remission for a considerable time and haven't had severe symptoms. However, when I mentioned my pain and related issues to my doctor, the response was always the same: "Lupus is painful." I am very familiar with the joint stiffness and swelling from my SLE. The exhaustion and widespread pain I felt were something different. I felt unheard. I began to feel as though everyone thought I was imagining things. Out of frustration, I searched on Google, not expecting answers but unsure what else to do, which is when I found Ubie. The Ubie symptom checker was user-friendly, and remarkably, as I progressed through the questions, I became hopeful that I would finally get the answer I was looking for. The symptom checker's questions were so spot-on. It identified several previously unconsidered factors as relevant based solely on my initial two reported symptoms. After downloading the report and consulting my physician, I felt well-prepared and confident presenting this information. My doctor concurred with Ubie's fibromyalgia callout and prescribed an antidepressant, which has proven beneficial. I express my sincere gratitude to the developers for providing this empowering tool.
(Apr 2, 2025)
Q.
Somatic Pain? Why Your Body Is Hurting & Medically Approved Next Steps
A.
Somatic pain is pain from the body’s tissues like muscles, joints, bones, ligaments, or skin, usually sharp or aching, easy to pinpoint, and often worse with movement, most often caused by strain, injury, or inflammation but sometimes linked to chronic or widespread conditions. Medically approved next steps include brief rest followed by gentle movement, ice for new injuries, heat for stiffness, short term OTC pain relievers, and physical therapy, while urgent care is needed for sudden severe pain, major injury, weakness or numbness, bowel or bladder changes, fever, chest pain, weight loss, or pain lasting weeks. There are several factors to consider. See below to understand more.
References:
* Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, Keefe FJ, Mogil BJ, Ringkamp M, Sluka KS, Song XJ, Stevens B, Treede RD, Woolf CJ, Zinboonyahgoon C. The revised IASP definition of pain: concepts, challenges, and future directions. Pain. 2020 Sep;161(9):1976-1982. doi: 10.1097/j.pain.0000000000001939. PMID: 32694314.
* Treede RD. Classification of chronic pain revisited. Pain. 2019 May;160 Suppl 1:S53-S59. doi: 10.1097/j.pain.0000000000001471. PMID: 31090623.
* Urits I, An D, Wesp B, Zhou R, Amgalan A, Oh C, Varrassi G, Viswanath O, Kaye AD. Pharmacological Management of Chronic Musculoskeletal Pain: An Update. Pain Ther. 2019 Oct;8(5):785-802. doi: 10.1007/s40122-019-00122-9. Epub 2019 Aug 22. PMID: 31440810; PMCID: PMC6824367.
* Urits I, An D, Wesp B, Zhou R, Amgalan A, Oh C, Varrassi G, Viswanath O, Kaye AD. Nonpharmacological Management of Chronic Musculoskeletal Pain. Pain Ther. 2019 Oct;8(5):803-821. doi: 10.1007/s40122-019-00123-8. Epub 2019 Aug 22. PMID: 31440809; PMCID: PMC6824368.
* Cohen SP, Vase L, Hooten WM. Chronic Pain Management: An Overview of Current and Future Pain Therapies. Anesthesiology. 2020 Jan;132(1):162-179. doi: 10.1097/ALN.0000000000002991. PMID: 31713437.
Q.
Always Aching? Why Your Body is Inflamed & Medically Approved Next Steps
A.
There are several factors to consider: chronic inflammation often explains always-aching symptoms like widespread pain, stiffness, fatigue, and brain fog, with common drivers including autoimmune disease, chronic stress, poor sleep, ultra-processed diets, excess weight, inactivity, and other conditions. Medically approved next steps include improving sleep, following an anti-inflammatory eating pattern, moving regularly, managing stress, gradual weight loss if needed, reviewing medications with a clinician, and seeking evaluation for tests like CRP and ESR plus targeted treatments, and there are important red flags and nuances that could change your plan, so see the complete details below.
References:
* Liu Y, Zhang S, Song X, Liu C. Chronic inflammation: molecular mechanisms and therapeutic implications. Eur J Med Chem. 2021 Jul 22;223:113615. doi: 10.1016/j.ejmech.2021.113615. Epub ahead of print. PMID: 34293525.
* Krishnan V, Poudyal A, Vaddi R, Jain S, Taneja A, Kumar R, Kumar V. Systemic inflammation, pain, and their interrelationships: a narrative review. J Clin Transl Res. 2021 Sep 30;7(5):713-718. doi: 10.18053/jctres/v7i5/713. PMID: 34661066; PMCID: PMC8516104.
* Koutsokeras T, Manousaki D, Charakidas P, Chaniotis D, Kalokyris D. Dietary Patterns and Chronic Pain: A Narrative Review. Nutrients. 2021 Oct 19;13(10):3655. doi: 10.3390/nu13103655. PMID: 34684534; PMCID: PMC8538259.
* Handschin C. Exercise as an anti-inflammatory therapy. Cell Metab. 2023 Jul 4;35(7):1094-1100. doi: 10.1016/j.cmet.2023.06.002. PMID: 37402488.
* Myles A, Shah N, Al-Hashimi I, Al-Qadi A, Al-Jabri M, Al-Maashari A, Al-Qudsi M, Al-Mamari A. Lifestyle modifications for chronic inflammatory diseases: a systematic review. World J Clin Cases. 2021 Aug 6;9(22):6162-6178. doi: 10.12998/wjcc.v9.i22.6162. PMID: 34541221; PMCID: PMC8374921.
Q.
Is It Just Cold Symptoms? Why Your Body Hurts & Medically Approved Next Steps
A.
There are several factors to consider. Body aches with a cold are usually from your immune response, mild inflammation, or a low fever and tend to ease in 3 to 5 days, but severe or sudden aches, high or persistent fever, trouble breathing, chest pain, confusion, or symptoms lasting more than 10 days can signal flu, COVID, dehydration, bacterial infection, or another condition that needs medical care. Start with rest, fluids, acetaminophen or ibuprofen, warm showers, gentle stretching, and humidified air, and seek urgent care for the red flags detailed below; see below for the complete checklist, recovery timelines, when to call a doctor, and other key details that could change your next steps.
References:
* Turner RB. Common Cold and Flu: A Review of Pathophysiology, Differential Diagnosis, and Treatment. N Engl J Med. 2021 Oct 14;385(16):1488-1498.
* Gupta V, et al. Influenza: Diagnosis and Treatment. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. PMID: 32310574.
* Pinto-Pereira SM, et al. Management of Acute Respiratory Illness in Adults: A Review. JAMA. 2023 Mar 14;329(10):835-846.
* López-Benito P, et al. Musculoskeletal manifestations of viral infections. Open Forum Infect Dis. 2021 Jun 12;8(8):ofab272.
* Llor C, et al. Self-care in patients with symptoms of acute respiratory tract infection: a narrative review. J Clin Med. 2023 Feb 1;12(3):1219.
Q.
Is it Lyme? Why your body is aching and the medical steps to take now.
A.
There are several factors to consider: Lyme often presents within 3 to 30 days with a gradually expanding rash, fever, fatigue, headache, and aching muscles or joints, but other causes of whole‑body pain are common too. Next steps now: track symptoms and exposure and seek prompt care for a spreading rash, joint swelling, facial drooping, chest pain, or persistent flu‑like illness. Doctors may treat based on exam and timing because very early blood tests can be negative; more on diagnosis nuances, red flags, and prevention is below.
References:
* Chatzidionysiou A, Erbelding EJ. Lyme disease: a review of epidemiology, clinical features, and management. J Clin Rheumatol. 2022 Dec 1;28(8S):e720-e726. doi: 10.1097/RHU.0000000000001890. PMID: 36762391.
* Mead PS. Diagnosis and treatment of Lyme disease. Infect Dis Clin North Am. 2020 Jun;34(2):227-243. doi: 10.1016/j.idc.2020.03.003. Epub 2020 Apr 23. PMID: 32493504.
* Bockenstedt LK, Wormser GP. Pathogenesis and Immune Responses in Lyme Disease. Infect Dis Clin North Am. 2020 Jun;34(2):165-182. doi: 10.1016/j.idc.2020.03.001. Epub 2020 Mar 27. PMID: 32493503.
* Sanchez E, Sharma B, Kane I, Auwaerter PG. Update on the Diagnosis and Management of Lyme Disease. JAMA. 2019 Apr 23;321(16):1597-1607. doi: 10.1001/jama.2019.3807. PMID: 31017950.
* Radolf JD, Coyle PK, Greenstein PM, Landa P, Li F, Sze G, Wormser GP. Post-Treatment Lyme Disease Syndrome: A Systematic Review of Diagnosis and Management. Diagnostics (Basel). 2021 Oct 15;11(10):1904. doi: 10.3390/diagnostics11101904. PMID: 34679507.
Q.
Always in pain? Why your body is failing: Ehlers-Danlos Syndrome medical steps
A.
There are several factors to consider if you are always in pain; Ehlers-Danlos syndrome, a collagen disorder causing joint hypermobility, fragile tissues, and fatigue, is a key possibility that can explain widespread, activity-worsened pain. See below to understand more. Core next steps include documenting symptoms, getting a clinical evaluation for EDS criteria such as Beighton scoring with genetic testing for select types, seeking referrals to genetics, rheumatology, and cardiology as needed, starting stabilization-focused physical therapy and individualized pain management, and knowing urgent red flags, especially with suspected vascular EDS. For the full picture and guidance that could change your next steps, see the complete details below.
References:
* Malfait F, Francomano JM, Byers PH, Belmont J, Berglund B, Black J, Bloom L, Bowen JM, Brady AF, Brenton-Rule A, Carey JC, Chaudhury S, Chiarelli N, Colombi M, Demirdas D, De Backer L, De Paepe A, D'Hondt S, Doolin MT, Draper T, Ferrim DN, Fikree A, Filipovic-Sadic S, Fink C, Fohn A, Fraser G, G Graham H, Grant PK, Gulcelik NE, Grahame R, Hakim AJ, Jeunemaitre X, Johnson D, Johnston H, Juul-Kristensen B, Kapur S, Kennett R, Kosho T, Lavelle J, Le Merrer M, Loeys B, Lowe ME, Lundy H, Lyons H, McDonnell A, Mercer CL, Merrill L, Mogavero E, Morrison PJ, Nampoothiri S, Neves M, Oncel-Eskicioglu M, Parapia LA, Pepin M, Plaxton L, Pollin TI, Pruchno-Naveh N, Quigley E, Quintos RF, Rakovich M, Ramirez N, Randle N, Reader M, Rochester H, Rohrbach M, Ruiz-Santiago J, van Reijen HW, Sarda P, Savarirayan R, Schrader R, Schwartz SA, Simmonds EJ, Sobey GJ, Sobo V, Spriggs M, Star RA, Steiner RD, Stoler L, Sykes B, Thomas N, Tsipouras P, Vilain C, Vogt J, Wagner M, Wakeling EL, Wands TJ, Weiker GG, Wilcox WR, Williams M, Wincup C, Wise B, Wolfarth M, Yetman AT, Zschocke J, Tinkle B. The 2017 international classification of the Ehlers-Danlos Syndromes. Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):8-26. doi: 10.1002/ajmg.c.31552. Epub 2017 Jan 31. PMID: 28306017. https://pubmed.ncbi.nlm.nih.gov/28306017/
* Chopra P, Tinkle B, Hamonet C, Brock I, Gompel A, Bulbena A, Francomano C. Pain management in the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):212-219. doi: 10.1002/ajmg.c.31553. Epub 2017 Feb 21. PMID: 28306016. https://pubmed.ncbi.nlm.nih.gov/28306016/
* Levy HP. Hypermobile Ehlers-Danlos Syndrome. 2004 Feb 27 [Updated 2023 Feb 16]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. PMID: 20301456. https://pubmed.ncbi.nlm.nih.gov/20301456/
* Malfait F, Castori M, Hakim A, Francomano CA. Diagnosis, natural history, and management of Hypermobile Ehlers-Danlos Syndrome: A narrative review. Semin Cell Dev Biol. 2024 Jan;148:101783. doi: 10.1016/j.semcdb.2023
Q.
Is It Normal? Why Your Body Is Hurting & Medically Approved Next Steps
A.
There are several factors to consider. See below to understand more. Mild aches from overuse, viral infections, or stress are common and often improve with rest, hydration, gentle movement, good sleep, and short-term OTC pain relievers, but if pain lasts more than two weeks, worsens, interferes with life, or comes with red flags like chest pain, shortness of breath, high fever, confusion, stiff neck with fever, one-sided weakness, or limb swelling, seek care promptly; patterns tied to cycles or pelvic symptoms point to a gynecologist, and persistent widespread pain may relate to fibromyalgia, autoimmune disease, hormonal shifts, ME/CFS, or vitamin and iron deficiencies, with tests, step-by-step next actions, lifestyle changes, and a symptom checker detailed below.
References:
* Sakai, L. J., & Benyamin, R. M. (2022). Chronic Pain Management for Primary Care Providers: Current State of Evidence. *Pain and Therapy, 11*(3), 519–538.
* Schug, S. A., & Tawfik, M. M. (2021). Acute pain management in adults: a narrative review. *F1000Research, 10*, 1097.
* Nussbaum, E. B., & Papanastasiou, T. (2022). Diagnosis and Management of Common Musculoskeletal Pain Conditions. *Seminars in Plastic Surgery, 36*(01), 001–009.
* Chou, R., & Wipperman, M. (2022). Pain Assessment and Management: What Is the Role of the Primary Care Clinician? *Medical Clinics of North America, 106*(2), 329–343.
* Mapplebeck, J. C., & Basbaum, A. I. (2023). Pathophysiology of pain: new insights and treatment implications. *Pain, 164*(7), 1435-1444.
Q.
Is it Lyme Disease? Why Your Body is Aching & Medically Approved Steps
A.
Body-wide aches have many causes, and Lyme disease is one possibility after tick exposure in high risk areas. Key clues include flu-like fever and fatigue, muscle and joint pain, and a spreading rash, with early antibiotics usually very effective. There are several factors to consider that can change your next steps, including risk checks, urgent red flags, how and when tests help, and what treatment and prevention look like; see the complete guidance below to understand more.
References:
* Kohlman JS, Neppl S, Coyle B, Branda JA. Review of Lyme disease: clinical features, diagnosis, and treatment. *Curr Opin Infect Dis*. 2021 Jun 1;34(3):214-222. doi: 10.1097/QCO.0000000000000735. PMID: 34107567.
* Steere AC, Strle F, Wormser GP, et al. Musculoskeletal manifestations of Lyme disease. *Arthritis Rheumatol*. 2018 Sep;70(9):1359-1368. doi: 10.1002/art.40522. Epub 2018 Aug 6. PMID: 29514782.
* Aucott JN. Update on the diagnosis and treatment of Lyme disease. *N C Med J*. 2017 Jan-Feb;78(1):56-59. doi: 10.18049/ncjm.78.1.56. PMID: 28087968.
* Branda JA, Strle F, Strle K, et al. Lyme Disease: Clinical Spectrum and Diagnostic Challenges. *Clin Chem*. 2021 Jun 1;67(6):830-838. doi: 10.1093/clinchem/hvab010. PMID: 33924370.
* Pezzoni G, Pezzoni P, Rossi F, et al. Diagnosis and Management of Post-Treatment Lyme Disease Syndrome: A Review. *Clin Drug Investig*. 2021 Jun;41(6):531-540. doi: 10.1007/s40261-021-01031-2. Epub 2021 Mar 30. PMID: 33800885.
Q.
Body Aching? Why Your System is Crashing & Medically Approved Tamiflu Steps
A.
Sudden, deep body aches with fever, chills, and fatigue often signal the flu as your immune system surges; Tamiflu (oseltamivir) targets influenza and works best when started within 48 hours, typically 75 mg twice daily for 5 days, to shorten illness and lower complication risk. There are several factors to consider, including who should take it, possible side effects, the supportive steps that actually ease aches, and urgent warning signs; see below to understand more.
References:
* Michael, J. D. (2020). Pathogenesis of influenza virus infections. *Respiratory Medicine*, 172, 106103. PMID: 32800181.
* Ison, M. G. (2021). Oseltamivir Treatment for Influenza: A Review of Efficacy and Safety. *Infectious Diseases and Therapy*, 10(1), 1–14. PMID: 33300171.
* Teijaro, J. R. (2018). Host immune responses to influenza virus infection. *Trends in Immunology*, 39(12), 990–1002. PMID: 30424915.
* Dunning, J. W., et al. (2021). Clinical management of influenza: a review of current evidence and recommendations. *The Lancet Respiratory Medicine*, 9(1), 60–72. PMID: 33130095.
* Ohta, H., et al. (2021). Influenza-induced myalgia: an update on its pathogenesis. *Journal of Clinical Neuroscience*, 83, 169–174. PMID: 33303493.
Q.
Is Your Body Storing Stress? The Somatic Meaning Behind Left-Sided Pain (And What to Do)
A.
Left-sided pain can reflect how stress affects the nervous system and muscles, creating real somatic symptoms, yet it should not be assumed to be just stress. There are several factors to consider, including urgent red flags and practical steps like getting medical clarity, calming the nervous system, and combining physical and emotional care; see below for complete details that can guide your next healthcare decisions.
References:
* Hsu, M. C., & Chen, J. R. (2020). The stress response and its effect on musculoskeletal pain: a narrative review. *Pain and Therapy*, *9*(3), 429–439.
* van der Klaauw, A. A., & Veldman-Koopman, C. (2020). Psychological Stress and Functional Somatic Syndromes. *Frontiers in Psychiatry*, *11*, 807.
* Sar, V. (2019). Somatization and Somatic Symptom Disorder: A Review. *Psychotherapy and Psychosomatics*, *88*(2), 65–78.
* Falsafi, P., Arredondo, E. M., & Sallis, J. F. (2016). Mind-Body Interventions for Pain: a Systematic Review. *Psychosomatic Medicine*, *78*(7), 803–821.
* Sorge, R. E., & Totsch, S. K. (2017). Stress and the development of chronic pain. *Neuroscience Bulletin*, *33*(1), 1–13.
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