Osteoarthritis vs Rheumatoid Arthritis Quiz

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Joint pain

Inflammation in joints

Stiffness all over body

Joint pain on both sides of the body

Exercise makes pain worse

Body stiff in the mornings

Pain in both hands

Mouth ulcers

Swollen joints in fingers

Body pain

Rash on face

Joint swelling

Not seeing your symptoms? No worries!

Overview

Osteoarthritis (OA) and rheumatoid arthritis (RA) both cause joint pain and stiffness but differ in cause and pattern. OA is a degenerative condition caused by cartilage wear and typically affects older adults, while RA is an autoimmune disease that causes inflammation in the joints and may also impact other organs. RA tends to progress more rapidly and symmetrically.

Disease Summaries

Osteoarthritis: This is caused by wear and tear of the joint cartilage over time. Risk factors include repetitive joint movements and carrying heavy loads for many years.

Rheumatoid Arthritis: This is a chronic inflammatory disease where the body's immune system attacks multiple joints, most commonly in the hands and feet. The cause and trigger is unknown.

Comparing Symptoms

Overlapping Symptoms

  • Joint pain and stiffness
  • Decreased range of motion
  • Swelling (occasionally)
  • Symptoms worsen with age
  • Impact on daily activities

Osteoarthritis Specific Symptoms

  • Pain worsens with activity and improves with rest
  • Stiffness usually lasts less than 30 minutes
  • Affects weight-bearing joints (knees, hips, spine) and hands
  • Bone spurs and joint deformities
  • Gradual onset due to wear and tear

Rheumatoid Arthritis Specific Symptoms

  • Pain and stiffness often worse in the morning or after rest
  • Stiffness lasts longer than 30 minutes
  • Symmetrical joint involvement (both sides of the body)
  • Joint swelling, warmth, and redness
  • Autoimmune origin with systemic symptoms (fatigue, fever)

Treatment Approaches

Osteoarthritis Treatment Approaches

Osteoarthritis cannot be reversed, but treatment can improve its symptoms. Mild cases can be managed with lifestyle changes like losing weight, using walking aids, and warm compresses. Painkillers and medicine to reduce inflammation can help with joint pain - these can sometimes be injected directly into the joint. In severe cases, surgery to smooth the bone surface or replace it with an implant can be done.

Rheumatoid Arthritis Treatment Approaches

Treatment aims to reduce inflammation and long-term joint damage. Patients may be prescribed immune-suppressing medications and anti-inflammatory medications for pain. Physical exercise is also important for maintaining muscle strength and joint mobility. Smoking cessation and attention to diet are recommended.

Reviewed By:

Kenji Taylor, MD, MSc

Kenji Taylor, MD, MSc (Family Medicine, Primary Care)

Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.

Kaito Nakamura, MD

Kaito Nakamura, MD (Rheumatology)

Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.

From our team of 50+ doctors

Content updated on Apr 27, 2025

Following the Medical Content Editorial Policy

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