Hand-Foot Syndrome Quiz

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Reviewed By:

Unnati Patel

Unnati Patel, MD, MSc (GP / Family doctor)

Dr Patel graduated from the Zhejiang University School of Medicine. She worked in clinical research at the University of Illinois in Chicago and University of Nevada in Las Vegas focused on culturally adapted health interventions for preventive medicine in the community setting. Received her Master's of Science in Global Health (concentration in Health Policy) from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. Unnati went on to complete her family medicine residency in Chicago, Illinois at Norwegian American Hospital. | | She is currently working as a primary care physician in the city of Chicago and completing her Master's of Business Administration at the Northwestern University Kellogg School of Management and Fellowship in Leadership in Value-Based Care.

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

From our team of 50+ doctors

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With an easy 3-min questionnaire, Ubie's AI-powered system will generate a free report on possible causes.

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  • Hand-foot syndrome as well as similar diseases can be checked at the same time.

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✔︎  When to see a doctor

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People with these symptoms also use Ubie's symptom checker to find possible causes

  • My fingers and toes have turned red

  • Skin problem in an area that was exposed to a heater or warming device for a long time

  • Bumpy rash that started on the neck, then spread to the rest of the body

  • Firm flesh-colored papules with visible capillaries on bilateral cheeks

  • A rash that appeared after a few days of feeling unwell / having fever

  • Bumpy rash that appeared, then rapidly spread to the rest of the body

  • Pain in the region, followed by red spots and blisters 2-3 days later

Just 3 minutes.
Developed by doctors.

Learn more about Hand-foot syndrome

Content updated on Sep 20, 2022

What is hand-foot syndrome?

Hand-foot syndrome is a side effect of some cancer chemotherapy drugs that can cause redness, swelling and blistering on the palms of the hands and soles of the feet. It tends to appear within the first 2 to 3 months of treatment.

Symptoms of hand-foot syndrome

  • Skin redness or red bumpy rashes

  • Change in nail color

  • Scaly skin that flakes off

  • Blisters

Questions your doctor may ask to check for hand-foot syndrome

Your doctor may ask these questions to diagnose hand-foot syndrome

  • Do you have red skin or red spots on the skin?

  • Has your nail color changed?

  • Do you have scaly skin that flakes off?

  • Do you have blisters on your skin?

Treatment for hand-foot syndrome

Hand-foot syndrome treatment is mainly symptomatic with the help of oral pain killers and numbing creams, ointments. Sometimes, the dosage of chemotherapy may be adjusted if required.

View the symptoms of Hand-foot syndrome

Reviewed By:

Unnati Patel

Unnati Patel, MD, MSc (GP / Family doctor)

Dr Patel graduated from the Zhejiang University School of Medicine. She worked in clinical research at the University of Illinois in Chicago and University of Nevada in Las Vegas focused on culturally adapted health interventions for preventive medicine in the community setting. Received her Master's of Science in Global Health (concentration in Health Policy) from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. Unnati went on to complete her family medicine residency in Chicago, Illinois at Norwegian American Hospital. | | She is currently working as a primary care physician in the city of Chicago and completing her Master's of Business Administration at the Northwestern University Kellogg School of Management and Fellowship in Leadership in Value-Based Care.

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

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Just 3 minutes.
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