Hypergammaglobulinemic Purpura Quiz
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Learn more about Hypergammaglobulinemic purpura
Content updated on Nov 2, 2022
What is hypergammaglobulinemic purpura?
Hypergammaglobulinemic purpura of Waldenström is a condition characterized by hypergammaglobulinemia (high levels of immunoglobulins in the blood), recurring purpura (tiny red/ purple spots due to small blood vessels leaking into the skin), increased Erythrocyte Sedimentation Rate (indicating inflammation in the body) , and rheumatoid factors in the blood (proteins from the immune system that can attack healthy tissue). The cause is unknown, but may be associated with other diseases, like immune system disorders.
Symptoms of hypergammaglobulinemic purpura
Purple rash
Questions your doctor may ask to check for hypergammaglobulinemic purpura
Your doctor may ask these questions to diagnose hypergammaglobulinemic purpura
Do you have purple spots on your skin?
Treatment for hypergammaglobulinemic purpura
Hypergammaglobulinemic purpura treatment can vary dependng on the severity. Treatment involves medication to suppress inflammation and reduce symptoms.
View the symptoms of Hypergammaglobulinemic purpura
Diseases related to Hypergammaglobulinemic purpura
References
Gupta L, Edavalath S, Choudhary N, Aggarwal A. Hypergammaglobulinemic Purpura as the First Presentation of Juvenile Onset Sjögren Syndrome-Case-Based Review of Literature. J Clin Rheumatol. 2021 Dec 1;27(8S):S357-S361. doi: 10.1097/RHU.0000000000001582. PMID: 33298812.
https://journals.lww.com/jclinrheum/Citation/2021/12003/Hypergammaglobulinemic_Purpura_as_the_First.11.aspx
Finder KA, McCollough ML, Dixon SL, Majka AJ, Jaremko W. Hypergammaglobulinemic purpura of Waldenström. J Am Acad Dermatol. 1990 Oct;23(4 Pt 1):669-76. doi: 10.1016/0190-9622(90)70271-i. PMID: 2229494.
https://www.jaad.org/article/0190-9622(90)70271-I/pdf
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan